Brevinin-2HS2 peptide

Brevinin-2HS2 peptide

• Handling and Storage of Synthetic Peptides
• Material Safety Data Sheets (MSDS)

Batch to batch variation of the purity

SLLGTVKDLLIGAGKSAAQSVLKGLSGKLSKDC

Ser-Leu-Leu-Gly-Thr-Val-Lys-Asp-Leu-Leu-Ile-Gly-Ala-Gly-Lys-Ser-Ala-Ala-Gln-Ser-Val-Leu-Lys-Gly-Leu-Ser-Gly-Lys-Leu-Ser-Lys-Asp-Cys

33

97.8%

Synthetic

Powder

Active against Gram-positive S. aureus ATCC2592 (MIC 19 uM), B. licheniformis X39 (MIC 39 uM), R. rhodochrous X15 (MIC 9.5 uM), Gram-negative P. faecalis X29 (MIC 9.5 uM), and fungi S. mouldd 090223 and C. albicans ATCC2002 (MIC 19-37.5 uM). Poor hemolysis (LC50=300 uM). (Wang H et al. 2012 Peptides in press). Found in multiple species. Updated 1/4/12 GW. Brevinin-2HS2 has Antimicrobial activity. The source of Brevinin-2HS2 is Huia schmackeri (formerly Rana (Odorrana) schmackeri); Odorrana hainanensis, China, Asia.

Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides

• Quan Z, Zhou M, Chen W, Chen T, Walker B, Shaw C. Novel brevinins from Chinese piebald odorous frog (Huia schmackeri) skin deduced from cloned biosynthetic precursors. Peptides. 2008;29(8):1456-60.

Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.