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  • BQ 3020 peptide

BQ 3020 peptide

Not For Human Use, Lab Use Only.

Cat.#: 318977

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* Buy 1 get 1 free (?) What is TFA?

Special Price 135.90 USD

Availability: 1-2 weeks
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Product Information

  • Product Name
    BQ 3020 peptide
  • Documents

    Batch to batch variation of the purity

  • Sequence Shortening
    Ac-LMDKEAVYFAHLDIIW-OH
  • Sequence
    Ac-Leu-Met-Asp-Lys-Glu-Ala-Val-Tyr-Phe-Ala-His-Leu-Asp-Ile-Ile-Trp-OH
  • Length (aa)
    16
  • Peptide Purity (HPLC)
    95.36%
  • Molecular Formula
    C96H140N20O25S
  • Molecular Weight
    2006.31
  • Source
    Synthetic
  • Form
    Powder
  • Description
    BQ 3020 is a linear analogue of endothelin-1 (ET-1) which is a highly potent and selective ETB endothelin receptor agonist with Ki values of 0.18 and 970 nM at human ETB and ETA receptors. Intratumour administration of BQ 3020 can attenuate cancer pain by modulating β-endorphin release from squamous cell carcinoma cells in mouse models.
  • Storage Guidelines
    Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides
  • References
    • Ekelund et al (1994) Effects of selective ETB-receptor stimulation on arterial, venous and capillary functions in cat skeletal muscle. Br.J.Pharmacol. 112 887 PMID: 7921617
    • Strachan et al (2000) Constriction to ETB receptor agonists, BQ-3020 and sarafotoxin S6c, in human resistance and capacitance vessels in vivo. British J. Clinical Pharmacology 50: 27 PMID: 10886114
    • Quang and Schmidt (2010) Peripheral endothelin B receptor agonist-induced antinociception involves endogenous opioids in mice, PAIN 149(2) 254 PMID: 20206445
  • About TFA salt

    Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

    Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

    Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

    In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.

  • Molar Concentration Calculator

  • Dilution Calculator

  • Percent Concentration Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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• Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.

• Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.

• Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"