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  • Bmkn2 peptide

Bmkn2 peptide

Not For Human Use, Lab Use Only.

Cat.#: 312561

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* Buy 1 get 1 free (?) What is TFA?

Special Price 156.40 USD

Availability: 1-2 weeks
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Product Information

  • Product Name
    Bmkn2 peptide
  • Documents

    Batch to batch variation of the purity

  • Sequence Shortening
    FIGAIARLLSKIF-NH2
  • Sequence
    H-Phe-Ile-Gly-Ala-Ile-Ala-Arg-Leu-Leu-Ser-Lys-Ile-Phe-Gly-Lys-Arg-NH2
  • Length (aa)
    16
  • Peptide Purity (HPLC)
    95.8%
  • Molecular Weight
    1447.84
  • Source
    Synthetic
  • Form
    Powder
  • Description

    BmKn2 is an antimicrobial peptide originally characterized from the venom of the scorpion Mesobuthus martensii Karsch. It belongs to a class of cationic and amphiphilic peptides known for their ability to interact with microbial membranes.

    A derivative of this peptide, named Kn2-7, was designed to enhance its antibacterial properties. Kn2-7 exhibits increased inhibitory activity against both Gram-positive and Gram-negative bacteria compared to the wild-type BmKn2. The peptide exerts its bactericidal effect by rapidly binding to key components of the bacterial cell wall: lipoteichoic acid (LTA) in Staphylococcus aureus and lipopolysaccharides (LPS) in Escherichia coli. This interaction leads to disruption of the cell surface structure. Furthermore, the hemolytic activity of the Kn2-7 derivative is significantly reduced relative to the original BmKn2 peptide.

    BmKb1 and BmKn2 both are basic, α-helical peptide with an amidated C-terminus.
  • Storage Guidelines
    Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides
  • References
    • Zeng XC, Wang SX, Zhu Y, Zhu SY, Li WX. Identification and functional characterization of novel scorpion venom peptides with no disulfide bridge from Buthus martensii Karsch. Peptides. 2004;25(2):143-50.
  • About TFA salt

    Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

    Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

    Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

    In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.

  • Molar Concentration Calculator

  • Dilution Calculator

  • Percent Concentration Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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• Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.

• Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.

• Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"