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  • Human NGF / NGFB recombinant protein

Human NGF / NGFB recombinant protein

Cat.#: 502544

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Product Information

  • Product Name
    Human NGF / NGFB recombinant protein
  • Documents
  • Description
    Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival. Inhibits metalloproteinase dependent proteolysis of platelet glycoprotein VI (PubMed:20164177).
  • Protein name
    Beta-nerve growth factor
  • Protein short names
    MGC161428; NGF; BETA-NGF; NGFB; MGC161426; HSAN5
  • Uniprot ID
    P01138
  • Gene Name
    NGF; NGFB
  • Source/Expression Host
    CHO Stable Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the mature form of human ?-NGF (NP_002497.2) (Ser 122-Arg 239) was expressed.
  • Protein Species
    Human
  • Molecular weight
    The mature recombinant human ?-NGF consists of 118 amino acids and has a predicted molecular mass of 13.2 kDa. ?-NGF exists as a non-disulfide linked homodimer in solution.
  • Purity
    > 95 % as determined by SDS-PAGE
  • Activity
    Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. The ED50 for this effect is typically 0.2-2 ng/ml.
  • Validations

    Human ?-NGF / Beta-NGF Protein SDS-PAGE

    Human ?-NGF / Beta-NGF Protein SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"