Cart 2
  • beta-Endorphin [1-9] / β-Lipotropin (61-69) peptide

beta-Endorphin [1-9] / β-Lipotropin (61-69) peptide

Not For Human Use, Lab Use Only.

Cat.#: 307297

Size:

* Buy 1 get 1 free (?) What is TFA?

Special Price 182.10 USD

Availability: 1-2 weeks
- +

Add to cart to get an online quotation

Product Information

  • Product Name
    beta-Endorphin [1-9] / β-Lipotropin (61-69) peptide
  • Documents

    Batch to batch variation of the purity

  • Sequence Shortening
    YGGFMTSEK
  • Sequence
    Tyr-Gly-Gly-Phe-Met-Thr-Ser-Glu-Lys
  • Length (aa)
    9
  • Peptide Purity (HPLC)
    97.4%
  • Molecular Formula
    C45H66N10O15S
  • Molecular Weight
    1019.1
  • CAS No.
    59481-79-7
  • Source
    Synthetic
  • Form
    Powder
  • Description

    beta-Endorphin [1-9] / beta-Lipotropin (61-69) is a nonapeptide corresponding to amino acid residues 61 through 69 of the pituitary hormone beta-lipotropin. Its amino acid sequence is Tyr-Gly-Gly-Phe-Met-Thr-Ser-Glu-Lys. This fragment contains the Met-enkephalin pentapeptide sequence (residues 61-65) within its structure. Studies on the guinea-pig ileum longitudinal muscle strip have demonstrated that this peptide possesses opioid agonist activity, exhibiting a dose-response curve parallel to that of normorphine, though with approximately 2.5 times lower potency than normorphine. The inhibitory effects of this peptide are completely antagonized by the opioid antagonist naloxone.

  • Storage Guidelines
    Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides
  • References
    • Gráf L, Rónai A, Bajusz S, Csheh G, Székely JI. Opioid agonist activity of beta-lipotropin fragments: a possible biological source of morphine-like substances in the pituitary. FEBS Lett. 1976 Apr 15;64(1):181-4. doi: 10.1016/0014-5793(76)80278-5. PMID: 1269751.
  • About TFA salt

    Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

    Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

    Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

    In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.

  • Molar Concentration Calculator

  • Dilution Calculator

  • Percent Concentration Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight

• Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.

• Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.

• Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"