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Product Name
Recombinant BCL6B protein (His tag)
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Description
Recombinant Human BCL6B Protein Fragment (aa 325-479) – a highly stable and soluble fragment of the B-cell CLL/lymphoma 6 member B protein, designed for structural and biochemical studies. This fragment retains key properties for investigating transcriptional regulation mechanisms in early B-cell development.
The full-length BCL6B protein, encoded by the BCL6B gene, functions as a sequence-specific transcriptional repressor in association with BCL6. It plays a critical role in early B-cell development, potentially influencing specific stages or events during this process. The protein is localized to the nucleus, where it contributes to gene regulation. This recombinant fragment (aa 325-479) was selected based on computational predictions to ensure stability and solubility, enabling reliable experimental analysis of its structural and functional characteristics.
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Protein name
B-cell CLL/lymphoma 6 member B protein
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Uniprot ID
Q8N143
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Gene Name
BCL6B; BAZF; ZNF62
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
DNA encoding 325-479 aa (Q8N143) were fused with 6His tag.
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Protein Species
Human
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Molecular weight
Predictes a molecular mass of 19.44 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 19 kDa band.
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Purity
>88%, by SDS-PAGE with Coomassie Brilliant Blue staining.
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Activity
Not tested.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"