AtPep3 peptide

AtPep3 peptide

• Handling and Storage of Synthetic Peptides
• Material Safety Data Sheets (MSDS)

Batch to batch variation of the purity

H-EIKARGKNKTKPTPSSGKGGKHN-OH

H-Glu-Ile-Lys-Ala-Arg-Gly-Lys-Asn-Lys-Thr-Lys-Pro-Thr-Pro-Ser-Ser-Gly-Lys-Gly-Gly-Lys-His-Asn-OH

23

95.43%

C₁₀₂H₁₇₈N₃₆O₃₂

2420.71

Synthetic

Powder

AtPep3 is a hormone-like peptide that plays a role in the salinity stress tolerance of plants. It is encoded by the AtPROPEP3 gene, which is highly up-regulated in response to salinity stress . Synthetic peptides encoded by AtPROPEP3, including a C-terminal peptide fragment called AtPep3, have been shown to inhibit salt-induced bleaching of chlorophyll in seedlings, indicating their role in salinity stress tolerance. AtPep3 is recognized by the PEPR1 receptor and functions to increase salinity stress tolerance in plants. It is a member of the Pep family and acts as an elicitor peptide for immune response in plants . AtPROPEP1-7 genes, including AtPep3, are up-regulated in response to infections from pathogens or bacteria, and their binding with membrane-receptor kinase genes (PEPR1 and -2) is important for the immune response in Arabidopsis

Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides

• Nakaminami K, Okamoto M, Higuchi-Takeuchi M, Yoshizumi T, Yamaguchi Y, Fukao Y, Shimizu M, Ohashi C, Tanaka M, Matsui M, Shinozaki K, Seki M, Hanada K. AtPep3 is a hormone-like peptide that plays a role in the salinity stress tolerance of plants. Proc Natl Acad Sci U S A. 2018 May 29;115(22):5810-5815. doi: 10.1073/pnas.1719491115. Epub 2018 May 14. PMID: 29760074; PMCID: PMC5984501.

Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.