Arenicin-1 peptide

Arenicin-1 peptide

• COA/MS/HPLC Report
• Handling and Storage of Synthetic Peptides
• Material Safety Data Sheets (MSDS)

Batch to batch variation of the purity

RWCVYAYVRVRGVLVRYRRCW

H-Arg-Trp-Cys-Val-Tyr-Ala-Tyr-Val-Arg-Val-Arg-Gly-Val-Leu-Val-Arg-Tyr-Arg-Arg-Cys-Trp-OH (disulfide bond: Cys³-Cys²⁰)

21

95.14%

C₁₂₇H₁₉₃N₄₁O₂₅S₂

2758.2

808102-57-0

Synthetic

Powder

Arenicin-1 has Antibacterial activity. Arenicin-1 was found in Arenicola marina. The Arenicin-1 (AR-1:RWCVYAYVRVRGVLVRYRRCW), a novel 21-residue antimicrobial peptide, was purified from coelomocytes of the marine polychaeta Arenicola marina (lugworm). This class II antimicrobial peptide contains a single disulfide bridge between Cys3 and Cys20, forming a large 18-residue ring.

Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides

• Lee JU, Kang DI, Zhu WL, Shin SY, Hahm KS, Kim Y. Solution structures and biological functions of the antimicrobial peptide, arenicin-1, and its linear derivative. Biopolymers. 2007;88(2):208-16. doi: 10.1002/bip.20700. PMID: 17285588.

Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.