AQ-1766 peptide

AQ-1766 peptide

• Handling and Storage of Synthetic Peptides
• Material Safety Data Sheets (MSDS)

Batch to batch variation of the purity

H-LWFYTMWH-OH

H-Leu-Trp-Phe-Tyr-Thr-Met-Trp-His-OH

8

95.54%

C₆₁H₇₄N₁₂O₁₁S

1183.37

Synthetic

Powder

The peptide named AQ-1766 peptide (LWFYTMWH) derived from microalgae Tetraselmis suecica was active against both Gram-negative and positive pathogens, which includes S. typhimurium, E. coli, Bacillus cereus, Pseudomonas aeruginosa, and methicillin-resistant S. aureus (MRSA), respectively. The peptide (AQ-1766) derived from T. suecica by acid hydrolysates is having highest antibacterial activity against, L. monocytogenes, B. cereus, M. luteus, methicillin-resistant S. typhimurium, S. aureus, P. aeruginosa, and E. coli at a 10–50 μm concentration.

Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides

• Ayswaria R, Vijayan J, Nathan VK. Antimicrobial peptides derived from microalgae for combating antibiotic resistance: Current status and prospects. Cell Biochem Funct. 2023 Mar;41(2):142-151. doi: 10.1002/cbf.3779. Epub 2023 Feb 4. PMID: 36738178.

Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.