APOC1 peptide

APOC1 peptide

• Handling and Storage of Synthetic Peptides
• Material Safety Data Sheets (MSDS)

Batch to batch variation of the purity

FSTKTRNWFSEHFKKVKEKLKDTFA

Phe-Ser-Thr-Lys-Thr-Arg-Asn-Trp-Phe-Ser-Glu-His-Phe-Lys-Lys-Val-Lys-Glu-Lys-Leu-Lys-Asp-Thr-Phe-Ala

25

96.5%

Synthetic

Powder

The peptide was captured from alligator plasma by a custom-built functionalized hydrogel microparticles followed by de nono sequencing by mass spectrometer. This is a unique sequence since it shows 39.3% SIMILAR TO Latarcin 3b. A fragment of blood apolipoprotein C1. ApoC1(64-88) is active against E. coli, P. aeruginosa (EC50 0.192 and 1.41 uM), B. cereus, and S. aureus (EC50 0.245 and 9.66 uM). A further truncated fragment, apoC1(67-88), was also found to be slightly more active against these bacteria. APOC1 was found in plasma, the American Alligator, Alligator mississippiensis.

Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides

• Bishop BM, Juba ML, Devine MC, et al. Bioprospecting the American alligator (Alligator mississippiensis) host defense peptidome. PLoS ONE. 2015;10(2):e0117394.

Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.