Antimicrobial peptide, Gaegurin 5 [K17]
Three letter code
H-Phe-Leu-Gly-Ala-Leu-Phe-Lys-Val-Ala-Ser-Lys-Val-Leu-Pro-Ser-Val-Lys-Cys-Ala-Ile-Thr-Lys-Lys-Cys-OH (disulfide bond: Cys18-Cys24)
Peptide Purity (HPLC)
The source of Antimicrobial peptide, Gaegurin 5 [K17] is Korean wrinkled frog (Rana rugosa).
Ideally Antimicrobial peptide, Gaegurin 5 [K17] should be stored in a freezer at or below -9C. Antimicrobial peptide, Gaegurin 5 [K17] should be refrigerated after reconstitution. For more details, please refer to the manual:Handling and Storage of Synthetic Peptides
- Park JM, Jung JE, Lee BJ. Antimicrobial peptides from the skin of a Korean frog, Rana rugosa. Biochem Biophys Res Commun. 1994;205(1):948-54.
About TFA salt
Trifluoroacetic acid (TFA) is a strong acid, which is commonly used to cleave synthesized peptides from solid-phase resins and is also used to improve HPLC performance in the peptide purification step. By default, custom peptides are delivered as lyophilized TFA salts, and can contain as much as 10-45% TFA.
TFA in custom peptides can cause inexplicable discrepancies in subsequent assay data. For instance, TFA in nM concentrations has been shown to interfere with cellular assays, inhibiting cellular proliferation in some instances, and increasing cell viability in others . It has also been found to be an unintended allosteric modulator of the glycine receptor, GlyR.
TFA Removal Service is recommended for:
- Peptides that will be used in cellular assays
- Peptides that will be used as APIs or in manufactured products
- For hydrophilic peptides containing numerous basic residues
- Analysed Sequence:H-FLGALFKVASKVLPSVKCAITKKC-OH
- Chemical Formula:C119H201N29O28S2
- Sequence length:24
- Extinction coefficient:120 M-1cm-1
- Mw average:2550.17
- Theoretical pI:10.39
- Data Source:Peptide Property Calculator
GRAVY = grand average of hydropathy
Red: Hydrophobic uncharged residues, like F I L M V W A and P
Blue: Basic residues, like R K H and N-terminal -NH2
Green: Acidic residues, like D E and C-terminal -COOH
Black: Polar uncharged residues, like G S T C N Q and Y
Related Products / Services
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