antifouling zwitterionic peptide

antifouling zwitterionic peptide

• COA/MS/HPLC Report
• Handling and Storage of Synthetic Peptides
• Material Safety Data Sheets (MSDS)

Batch to batch variation of the purity

H-CFEFKFC-OH

H-Cys-Phe-Glu-Phe-Lys-Phe-Cys-OH

7

99.06%

C₄₄H₅₈N₈O₁₀S₂

923.1

Synthetic

Powder

It has the properties of antifouling zwitterionic peptide hydrogel, and can be used in fabricating electrochemical biosensors.The zwitterionic peptide hydrogel with cysteine terminal is easy for immobilization onto the gold surface, and it is also suitable for the immobilization of biomolecules such as antibodies, through the formation of covalent amide bonds. The peptide hydrogel possessed excellent antifouling property, and it was able to effectively prevent the adsorption of nonspecific proteins, cells and other biomolecules.

Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides

• Du Q, Wang W, Zeng X, Luo X. Antifouling zwitterionic peptide hydrogel based electrochemical biosensor for reliable detection of prostate specific antigen in human serum. Anal Chim Acta. 2023 Jan 25;1239:340674. doi: 10.1016/j.aca.2022.340674. Epub 2022 Nov 24. PMID: 36628704.

Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.