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Product Name
Human SNCA/alpha-Synuclein recombinant protein
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Description
May be involved in the regulation of dopamine release and transport. Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation.
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Protein name
Alpha-synuclein
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Protein short names
PD1; PARK1; MGC110988; PARK4; NACP; ALPHASYN
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Uniprot ID
P37840
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Gene Name
SNCA; NACP; PARK1
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the mature form of human SNCA isoform 1 (P37840-1) (Met 1-Ala 140) was expressed and purified.
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Protein Species
Human
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Molecular weight
The recombinant human SNCA consisting of 140 amino acids and has a calculated molecular mass of 14.5 kDa. It migrates as an approximately 19 kDa band in SDS-PAGE under reducing conditions.
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Purity
> 97 % as determined by SDS-PAGE
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Validations
Human SNCA / alpha-Synuclein Protein SDS-PAGE
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