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  • (Ala92)-Peptide 6

(Ala92)-Peptide 6

Not For Human Use, Lab Use Only.

Cat.#: 308277

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* Buy 1 get 1 free (?) What is TFA?

Special Price 253.00 USD

Availability: 1-2 weeks
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Product Information

  • Product Name
    (Ala92)-Peptide 6
  • Documents

    Batch to batch variation of the purity

  • Sequence Shortening
    DAAREGFLATLVVLHRAGAR
  • Sequence
    H-Asp-Ala-Ala-Arg-Glu-Gly-Phe-Leu-Ala-Thr-Leu-Val-Val-Leu-His-Arg-Ala-Gly-Ala-Arg-OH
  • Length (aa)
    20
  • Peptide Purity (HPLC)
    97.8%
  • Molecular Formula
    C93H155N31O26
  • Molecular Weight
    2123.45
  • Source
    Synthetic
  • Form
    Powder
  • Description
    The sequence of this 20-residue peptide corresponds to amino acids 84-103 of p16. This synthetic peptide interacts with the cyclin-dependent kinases cdk4 and cdk6, and inhibits the in vitro and in vivo phosphorylation of the retinoblastoma gene product pRb mediated by cdk4-cyclin D1. When coupled to a small peptide carrier molecule and applied directly to the tissue culture medium, it blocks entry into S phase in normal proliferating human HaCaT cells and in cells released from serum starvation.
  • Storage Guidelines
    Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides
  • References
    • R.Fahraeus et al., Curr. Biol., 6, 84 (1996)
  • About TFA salt

    Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

    Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

    Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

    In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.

  • Molar Concentration Calculator

  • Dilution Calculator

  • Percent Concentration Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration
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Volume
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Molecular Weight

Peptide Property

  • Analysed Sequence:H-DAAREGFLATLVVLHRAGAR-OH
  • Chemical Formula:C93H155N31O26
  • Sequence length:20
  • Extinction coefficient:0 M-1cm-1
  • GRAVY:0.32
  • Mw average:2123.41
  • Theoretical pI:10.77
  • Data Source:Peptide Property Calculator

GRAVY = grand average of hydropathy

X: Hydrophobic uncharged residues, like F I L M V W A and P

X: Basic residues, like R K H

X: Acidic residues, like D E

X: Polar uncharged residues, like G S T C N Q and Y

• Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.

• Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.

• Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"