Ala-6-fenycin peptide

Ala-6-fenycin peptide

• Handling and Storage of Synthetic Peptides
• Material Safety Data Sheets (MSDS)

Batch to batch variation of the purity

EKYTEAPEYI

Glu-Lys-Tyr-Thr-Glu-Ala-Pro-Glu-Tyr-Ile

10

96.2%

Synthetic

Powder

BLIS: bacteriocin-like inhibitory substances. An acyl chain (C15 to C17 carbons) is attached to E1, residue 2 is an ornithine (represented as K), and the carboxylic group of C-terminal I10 forms an ester bond with the side chain of Y3. Active against Gram-positive bacteria (B. subtilis, L. acidophilus ATCC 4356, B. linens, C. Wmi NCTC 7547, L. monocytogenes, L. innocua, B. cereus, L. innocua ATCC 33090, L. innocua 1572, L. ivanovii 5 NCTC 11007, L. seeligeri AC 82/4, L. welshimeri AC 73/2, (Motta et al., 2007b), and Gram-negative bacteria (S. Gallinarum, E. carotovora 413, A. hydrophila, P. haemolytica, P. haemolytica). Also inhibited the replication of viruses such as equine arteritis virus (EAV) and feline herpesvirus type 1 (FHV-1) by over 94%. Ala-6-fenycin was found in Bacillus sp. strain P34.

Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides

• Scopel e silva D, De castro CC, Da silva e silva F, et al. Antiviral activity of a Bacillus sp. P34 peptide against pathogenic viruses of domestic animals. Braz J Microbiol. 2014;45(3):1089-94.

Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.