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  • ACTH (4-10) peptide

ACTH (4-10) peptide

Not For Human Use, Lab Use Only.

Cat.#: 312087

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* Buy 1 get 1 free (?) What is TFA?

Special Price 141.80 USD

Availability: 1-2 weeks
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Product Information

  • Product Name
    ACTH (4-10) peptide
  • Documents

    Batch to batch variation of the purity

  • Sequence Shortening
    MEHFRWG
  • Sequence
    H-Met-Glu-His-Phe-Arg-Trp-Gly-OH
  • Length (aa)
    7
  • Peptide Purity (HPLC)
    98%
  • Molecular Formula
    C44H59N13O10S
  • Molecular Weight
    962.1
  • CAS No.
    4037/1/8
  • Source
    Synthetic
  • Form
    Powder
  • Description

    ACTH (4-10) is a melanocortin peptide fragment derived from adrenocorticotropic hormone. It acts as a melanocortin receptor agonist, primarily targeting central nervous system pathways. This peptide is involved in catabolic signal transduction within hypothalamic neuropeptidergic networks.

    Studies indicate that intranasal administration allows ACTH (4-10) to access the cerebrospinal fluid compartment, bypassing the bloodstream. Its central actions are associated with modulating specific neural signaling pathways, though the precise mechanisms remain under investigation.

  • Storage Guidelines
    Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides
  • References
    • H.L.Fehm et al., J. Clin. Endocrinol. Metab., 86, 1144 (2001)
    • M.Hallschmidt et al., J. Clin. Endocrinol. Metab., 91, 522 (2006)
    • M.Hallschmidt et al., Regul. Pept., 149, 79 (2008)
  • About TFA salt

    Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

    Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

    Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

    In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.

  • Molar Concentration Calculator

  • Dilution Calculator

  • Percent Concentration Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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• Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.

• Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.

• Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"