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  • Acetyl Tetrapeptide-3

Acetyl Tetrapeptide-3

Not For Human Use, Lab Use Only.

Cat.#: 319875

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* Buy 1 get 1 free (?) What is TFA?

Special Price 145.30 USD

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Product Information

  • Product Name
    Acetyl Tetrapeptide-3
  • Documents

    Batch to batch variation of the purity

  • Sequence Shortening
    Ac-KGHK-NH2
  • Sequence
    Ac-Lys-Gly-His-Lys-NH2
  • Length (aa)
    5
  • Peptide Purity (HPLC)
    95.1%
  • Molecular Formula
    C22H39N9O5
  • Molecular Weight
    509.612
  • CAS No.
    827306-88-7
  • Source
    Synthetic
  • Form
    Powder
  • Description

    Acetyl Tetrapeptide-3 is a synthetic peptide that has been studied in combination with other botanical extracts. In vitro research indicates that this peptide can stimulate the production of extracellular matrix proteins, such as hydroxyproline, collagen type 3, and laminin, within dermal papilla cells. This activity is associated with structural support for hair follicles.

    Further in vitro observations suggest Acetyl Tetrapeptide-3 may influence inflammatory pathways by decreasing the levels of certain pro-inflammatory cytokines. The peptide's mechanism is linked to supporting the cellular microenvironment of the follicle.

  • Storage Guidelines
    Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides
  • References
    • Lueangarun S, Panchaprateep R. An Herbal Extract Combination (Biochanin A, Acetyl tetrapeptide-3, and Ginseng Extracts) versus 3% Minoxidil Solution for the Treatment of Androgenetic Alopecia: A 24-week, Prospective, Randomized, Triple-blind, Controlled Trial. J Clin Aesthet Dermatol. 2020 Oct;13(10):32-37. Epub 2020 Oct 1. PMID: 33584955; PMCID: PMC7840088.
  • About TFA salt

    Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

    Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

    Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

    In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.

  • Molar Concentration Calculator

  • Dilution Calculator

  • Percent Concentration Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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• Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.

• Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.

• Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"