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  • Acetyl-Calpastatin(184-210)(human) peptide

Acetyl-Calpastatin(184-210)(human) peptide

Not For Human Use, Lab Use Only.

Cat.#: 319583

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* Buy 1 get 1 free (?) What is TFA?

Special Price 247.70 USD

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Product Information

  • Product Name
    Acetyl-Calpastatin(184-210)(human) peptide
  • Documents

    Batch to batch variation of the purity

  • Sequence Shortening
    Acetylation-APRLEIVPTMYIYKLSPTGSEKLEDER-NH2
  • Sequence
    Acetylation-Ala-Pro-Arg-Leu-Glu-Ile-Val-Pro-Thr-Met-Tyr-Ile-Tyr-Lys-Leu-Ser-Pro-Thr-Gly-Ser-Glu-Lys-Leu-Glu-Asp-Glu-Arg-NH2
  • Length (aa)
    27
  • Peptide Purity (HPLC)
    95.27%
  • Molecular Formula
    C142H230N36O44S
  • Molecular Weight
    3177.61
  • Source
    Synthetic
  • Form
    Powder
  • Description
    Acetyl-Calpastatin(184-210)(human) is a potent, selective, and reversible calpain inhibitor, and Negative Control is a control scramble peptide of Acetyl-Calpastatin(184-210)(human) (HY-P1081). The calpain-calpastatin system is a component in TRH-induced signal transduction and that calpain is the major protease involved in down-regulation.
  • Storage Guidelines
    Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides
  • References
    • Eto A, Akita Y, Saido TC, Suzuki K, Kawashima S. The role of the calpain-calpastatin system in thyrotropin-releasing hormone-induced selective down-regulation of a protein kinase C isozyme, nPKC epsilon, in rat pituitary GH4C1 cells. J Biol Chem. 1995 Oct 20;270(42):25115-20. doi: 10.1074/jbc.270.42.25115. PMID: 7559644.
  • About TFA salt

    Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

    Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

    Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

    In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.

  • Molar Concentration Calculator

  • Dilution Calculator

  • Percent Concentration Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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• Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.

• Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.

• Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"