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Recombinant ABL2 protein (His tag)

Recombinant ABL2 protein (His tag)

Cat.#: 542321

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Special Price 294.7 USD

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Product Information

  • Product Name
    Recombinant ABL2 protein (His tag)
  • Documents
  • Description

    Recombinant ABL2 Fragment (108-561): A high-purity, functional fragment of human Tyrosine-protein kinase ABL2, encompassing the SH2 and Protein kinase domains. This product is engineered for studying cytoskeleton remodeling, cell motility, and signaling pathways in research applications.

    Tyrosine-protein kinase ABL2 is a non-receptor kinase critical for cell growth, survival, and cytoskeleton dynamics. It regulates actin remodeling, cell adhesion, and motility by phosphorylating key proteins like MYH10, CTTN, and ARHGAP35. ABL2 also influences receptor endocytosis and T-cell migration, and is implicated in pathogen-induced actin reorganization. Located in the cytoplasm and cytoskeleton, it plays overlapping roles with ABL1 in physiological and pathological signaling cascades, making it a significant target for cellular and infectious disease research.

  • Protein name
    Tyrosine-protein kinase ABL2
  • Uniprot ID
    P42684
  • Gene Name
    ABL2; ABLL; ARG
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    DNA encoding 108-561 aa (P42684) were fused with 6His tag.
  • Protein Species
    Human
  • Molecular weight
    Predictes a molecular mass of 52.90 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 54 kDa band.
  • Purity
    >90%, by SDS-PAGE with Coomassie Brilliant Blue staining.
  • Activity
    Not tested.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"