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Product Name
Recombinant A1AG2 protein (His tag)
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Description
Recombinant Alpha-1-acid glycoprotein 2 (AGP 2) fragment (residues 19-201) is a high-quality, soluble protein derived from human ORM2, designed for structural and biochemical studies. This 183-amino acid fragment retains key functional regions, offering researchers a stable tool to investigate ligand binding and immune modulation.
Alpha-1-acid glycoprotein 2 (AGP 2), encoded by the ORM2 gene in humans, functions as a transport protein in the bloodstream, binding hydrophobic ligands, synthetic drugs, and influencing their distribution and availability. It plays a role in modulating immune system activity during the acute-phase reaction and is secreted into the extracellular space, making it relevant for studies on drug delivery and inflammatory responses.
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Protein name
Alpha-1-acid glycoprotein 2
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Uniprot ID
P19652
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Gene Name
ORM2; AGP2
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
DNA encoding 19-201 aa (P19652) were fused with C-terminal 6His tag.
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Sequence
MSKIKIPLCA NLVPVPITNA TLDRITGKWF YIASAFRNEE YNKSVQEIQA TFFYFTPNKT EDTIFLREYQ TRQNQCFYNS SYLNVQRENG TVSRYEGGRE HVAHLLFLRD TKTLMFGSYL DDEKNWGLSF YADKPETTKE QLGEFYEALD CLCIPRSDVM YTDWKKDKCE PLEKQHEKER KQEEGESLEH HHHHH
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Protein Species
Human
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Molecular weight
Predictes a molecular mass of 23.16 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 25 kDa band.
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Purity
>85%, by SDS-PAGE with Coomassie Brilliant Blue staining.
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Activity
Not tested.
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Validations
Recombinant A1AG2 protein (His tag) SDS-PAGE
M: Marker; Lane 1: A1AG2; Lane 2: BSA
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"