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Product Name
Synaptophysin antibody
- Documents
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Description
Synaptophysin Mouse Monoclonal antibody. Positive WB detected in Human brain. Positive IF detected in PC-12 cells. Observed molecular weight by Western-blot: 38kd
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Tested applications
ELISA, WB, IF
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Species reactivity
Human,Mouse, Rat; other species not tested.
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Alternative names
synaptophysin antibody; SYP antibody
- Immunogen
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Isotype
Mouse IgG3
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Preparation
This antibody was obtained by immunization of Synaptophysin recombinant protein (Accession Number: NM_003179). Purification method: Protein G purified.
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Clonality
Monoclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IF: 1:10-1:100
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Validations
human brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:107614(SYP antibody) at dilution of 1:500
Immunofluorescent analysis of PC-12 cells using Catalog No:107614(Synaptophysin; SYP Antibody) at dilution of 1:25 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Mouse IgG(H+L)
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Background
Synaptophysin (SYP, also known as major synaptic vesicle protein p38) is a 38-kDa integral membrane glycoprotein that regulates synaptic vesicle endocytosis. It is the most abundant synaptic vesicle protein by mass. Synaptophysin is present in neuroendocrine cells and neurons that participate in synaptic transmission. Synaptophysin is a useful marker for identification of neuroendocrine cells and neoplasms. (PMID: 3010302; 21658579)
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