-
Product Name
TRIM24 antibody
- Documents
-
Description
TRIM24 Mouse Monoclonal antibody. Positive WB detected in NIH/3T3 cells, HEK-293 cells, HeLa cells. Observed molecular weight by Western-blot: 116 kDa
-
Tested applications
ELISA, WB
-
Species reactivity
Human, Mouse; other species not tested.
-
Alternative names
hTIF1 antibody; PTC6 antibody; RING finger protein 82 antibody; RNF82 antibody; TF1A antibody; TIF1 antibody; TIF1 alpha antibody; TIF1A antibody; TIF1ALPHA antibody; TRIM24 antibody; tripartite motif containing 24 antibody
- Immunogen
-
Isotype
Mouse IgG1
-
Preparation
This antibody was obtained by immunization of TRIM24 recombinant protein (Accession Number: NM_015905). Purification method: Protein G purified.
-
Clonality
Monoclonal
-
Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
-
Storage instructions
Store at -20℃. DO NOT ALIQUOT
-
Applications
Recommended Dilution:
WB: 1:500-1:5000
-
Validations
NIH/3T3 cells were subjected to SDS PAGE followed by western blot with Catalog No:107643(TRIM24 Antibody) at dilution of 1:1000
-
Background
TRIM24, also named as RNF82, TIF1 and TIF1A, interacts selectively in vitro with the AF2-activating domain of the estrogen receptors. Association with DNA-bound estrogen receptors, it requires the presence of estradiol. It is a regulation protein of P53. Defects in TRIM24 are a cause of thyroid papillary carcinoma (TPC) wich is a common tumor of the thyroid that typically arises as an irregular, solid or cystic mass from otherwise normal thyroid tissue.
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"