TBP antibody

TBP antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

TBP Rabbit Polyclonal antibody. Positive WB detected in Jurkat cells, COLO 320 cells, HeLa cells, mouse colon tissue, SKOV-3 cells. Positive IF detected in MCF-7 cells. Observed molecular weight by Western-blot: 46kd

ELISA, WB, IF

Human, Mouse; other species not tested.

GTF2D antibody; GTF2D1 antibody; SCA17 antibody; TATA binding factor antibody; TATA box binding protein antibody; TATA box factor antibody; TATA sequence binding protein antibody; TBP antibody; TF2D antibody; TFIID antibody

Rabbit IgG

This antibody was obtained by immunization of TBP recombinant protein (Accession Number: NM_003194). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

TBP, TATA box-binding protein, is a DNA-binding subunit of TFIID, which is a multisubunit complex essential for the expression of most protein-encoding genes. The well-conserved C-terminal domains of 180 aa is both necessary and sufficient for interaction with DNA and for assembly of the basal transcription apparatus.The N terminus of TBP modulates the DNA-binding activity of the C terminus of the protein. Once binds to the TATA box mediated by TBP, TFIID initiate the transcription step of the pre-initiation complex(PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II. This is a rabbit polyclonal antibody raised against part of N-terminal chain of human TBP, and specially recognize a ~46 kDa band.