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Product Name
SAR1A antibody
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Description
SAR1A Rabbit Polyclonal antibody. Positive IHC detected in human skeletal muscle tissue. Positive WB detected in HepG2 cells, HeLa cells, HT-1080 cells, mouse kidney tissue. Observed molecular weight by Western-blot: 23-25 kDa
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
COPII assOCiated small GTPase antibody; GTP binding protein SAR1a antibody; masra2 antibody; SAR1 antibody; SAR1 homolog A (S. cerevisiae) antibody; SAR1A antibody; Sara antibody; SARA1 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of Peptide (Accession Number: NM_020150). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IHC: 1:20-1:200
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Validations
HepG2 cells were subjected to SDS PAGE followed by western blot with Catalog No:115065(SAR1A antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human skeletal muscle slide using Catalog No:115065(SAR1A Antibody) at dilution of 1:50
Immunohistochemistry of paraffin-embedded human skeletal muscle slide using Catalog No:115065(SAR1A Antibody) at dilution of 1:50
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Background
SAR1A, also named as SAR1, SARA and SARA1, belongs to the small GTPase superfamily and SAR1 family. It is involved in transport from the endoplasmic reticulum to the Golgi apparatus. SAR1A is required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining endoplasmic reticulum exit sites (ERES). The antibody is specific to SAR1A.
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