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RAP1B-Specific antibody

Cat.#: 114545

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Special Price 239.0 USD

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Product Information

  • Product Name
    RAP1B-Specific antibody
  • Documents
  • Description
    RAP1B-Specific Rabbit Polyclonal antibody. Positive WB detected in human brain tissue, A549, mouse brain tissue. Observed molecular weight by Western-blot: 21 kDa
  • Tested applications
    ELISA, WB
  • Species reactivity
    Human,Mouse,Rat; other species not tested.
  • Alternative names
    DKFZp586H0723 antibody; GTP binding protein smg p21B antibody; K REV antibody; RAL1B antibody; RAP1B antibody; Ras related protein Rap 1b antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of RAP1B-Specific recombinant protein (Accession Number: NM_001010942). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:1000

  • Validations

    human brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:114545(RAP1B antibody) at dilution of 1:300

    human brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:114545(RAP1B antibody) at dilution of 1:300

    A549 cells were subjected to SDS PAGE followed by western blot with Catalog No:114545(RAP1B antibody) at dilution of 1:300. (Data provided by Angran Biotech (www.miRNAlab.com)).

    A549 cells were subjected to SDS PAGE followed by western blot with Catalog No:114545(RAP1B antibody) at dilution of 1:300. (Data provided by Angran Biotech (www.miRNAlab.com)).

  • Background
    RAP1B is a member of the RAS-like small GTP-binding protein superfamily. Members of this family regulate multiple cellular processes including cell adhesion and growth and differentiation. RAP1B localizes to cellular membranes and has been shown to regulate integrin-mediated cell signaling. It also plays a role in regulating outside-in signaling in platelets. The antibody is specific to RAP1B.
  • References
    • Guo H, Hu X, Ge S, Qian G, Zhang J. Regulation of RAP1B by miR-139 suppresses human colorectal carcinoma cell proliferation. The international journal of biochemistry & cell biology. 44(9):1465-72. 2012.
    • Sheng Y, Ding S, Chen K. Functional analysis of miR-101-3p and Rap1b involved in hepatitis B virus-related hepatocellular carcinoma pathogenesis. Biochemistry and cell biology = Biochimie et biologie cellulaire. 92(2):152-62. 2014.
    • Peng H, Luo J, Hao H. MicroRNA-100 regulates SW620 colorectal cancer cell proliferation and invasion by targeting RAP1B. Oncology reports. 31(5):2055-62. 2014.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"