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Product Name
Human RAP1B Recombinant protein (His tag)
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Description
GTP-binding protein that possesses intrinsic GTPase activity. Contributes to the polarizing activity of KRIT1 and CDH5 in the establishment and maintenance of correct endothelial cell polarity and vascular lumen. Required for the localization of phosphorylated PRKCZ, PARD3 and TIAM1 to the cell junction. Plays a role in the establishment of basal endothelial barrier function. {PubMed:18660803, PubMed:20332120, PubMed:21840392}.
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Protein name
Ras-related protein Rap-1b
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Uniprot ID
P61224
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Gene Name
RAP1B; OK/SW-cl.11
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human RAP1B (NP_056461.1) 1-184 aa was fused with the polyhistidine tag
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Protein Species
Human
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Activity
Not tested.
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Validations
Recombinant human RAP1B(Full length) SDS-PAGE
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