RABEPK antibody

Cat.#: 114495

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Product Information

  • Product Name
    RABEPK antibody
  • Documents
  • Description
    RABEPK Rabbit Polyclonal antibody. Positive WB detected in HeLa cells. Observed molecular weight by Western-blot: 44kd
  • Tested applications
    ELISA, WB
  • Species reactivity
    human, mouse, rat; other species not tested.
  • Alternative names
    RABEPK antibody; DKFZp686P1077 antibody; RAB9P40 antibody; bA65N13.1 antibody; 40 kDa Rab9 effector protein antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of RABEPK recombinant protein (Accession Number: NM_001174152). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:2000

  • Validations

    HeLa cells were subjected to SDS PAGE followed by western blot with Catalog No:114495(RABEPK antibody) at dilution of 1:500

    HeLa cells were subjected to SDS PAGE followed by western blot with Catalog No:114495(RABEPK antibody) at dilution of 1:500

  • Background
    Rab9 GTPase is required for the transport of mannose 6-phosphate receptors from endosomes to the trans-Golgi network in living cells, and in an in vitro system that reconstitutes this process. P40 is an effector of Rab9 that interacts preferentially with the active form of Rab9. p40 does not interact with Rab7 or K-Ras; it also fails to bind Rab9 when it is bound to GDI. The protein is found in cytosol, yet a significant fraction (~30%) is associated with cellular membranes. P40 is a very potent transport factor in that the pure, recombinant protein can stimulate, significantly, an in vitro transport assay that measures transport of mannose 6-phosphate receptors from endosomes to the trans-Golgi network.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"