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RAB4A antibody

Cat.#: 114452

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Product Information

  • Product Name
    RAB4A antibody
  • Documents
  • Description
    RAB4A Rabbit Polyclonal antibody. Positive WB detected in fetal human brain tissue, HeLa cells, mouse brain tissue, rat brain tissue. Positive IF detected in NIH/3T3 cells. Observed molecular weight by Western-blot: 26 kDa
  • Tested applications
    ELISA, WB, IF
  • Species reactivity
    Human,Mouse,Rat; other species not tested.
  • Alternative names
    HRES 1/RAB4 antibody; RAB4 antibody; RAB4A antibody; Ras related protein Rab 4A antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of RAB4A recombinant protein (Accession Number: NM_004578). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:1000

    IF: 1:20-1:200

  • Validations

    fetal human brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:114452(RAB4A Antibody) at dilution of 1:300

    fetal human brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:114452(RAB4A Antibody) at dilution of 1:300

    Immunofluorescent analysis of (-20oc Ethanol) fixed NIH/3T3 cells using Catalog No:114452(RAB4A Antibody) at dilution of 1:50 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

    Immunofluorescent analysis of (-20oc Ethanol) fixed NIH/3T3 cells using Catalog No:114452(RAB4A Antibody) at dilution of 1:50 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

  • Background
    The human RAB genes share structural and biochemical properties with the Ras gene superfamily, and RAB4 (synonym: RAB4A) is a small GTPase belonging to this Ras superfamily. Accumulating data suggests an important role for RAB proteins either in endocytosis or in biosynthetic protein transport. The transport of newly synthesized proteins from endoplasmic reticulum to the Golgi complex and to secretory vesicles involves the movement of carrier vesicles, a process that appears to involve RAB protein function. RAB4 may also function as regulator along the receptor recycling pathway.
  • References
    • Yamasaki T, Baron GS, Suzuki A, Hasebe R, Horiuchi M. Characterization of intracellular dynamics of inoculated PrP-res and newly generated PrP(Sc) during early stage prion infection in Neuro2a cells. Virology. 450-451:324-35. 2014.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"