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Product Name
Human EBP1/PA2G4 (His Tag) recombinant protein
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Description
May play a role in a ERBB3-regulated signal transduction pathway. Seems be involved in growth regulation. Acts a corepressor of the androgen receptor (AR) and is regulated by the ERBB3 ligand neuregulin-1/heregulin (HRG). Inhibits transcription of some E2F1-regulated promoters, probably by recruiting histone acetylase (HAT) activity. Binds RNA. Associates with 28S, 18S and 5.8S mature rRNAs, several rRNA precursors and probably U3 small nucleolar RNA. May be involved in regulation of intermediate and late steps of rRNA processing. May be involved in ribosome assembly. Mediates cap-independent translation of specific viral IRESs (internal ribosomal entry site) (By similarity). Regulates cell proliferation, differentiation, and survival. Isoform 1 suppresses apoptosis whereas isoform 2 promotes cell differentiation (By similarity).
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Protein name
Proliferation-associated protein 2G4
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Protein short names
hG4-1
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Uniprot ID
Q9UQ80
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Gene Name
PA2G4; EBP1
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human PA2G4 (Q9UQ80) (Ser 2-Asp 394) was expressed, with a polyhistide tag at the N-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human PA2G4 consisting of 404 amino acids and has a calculated molecular mass of 45.2 kDa. It migrates as an approximately 32 KDa band in SDS-PAGE under reducing conditions.
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Purity
> 92 % as determined by SDS-PAGE
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Validations
Human EBP1 / PA2G4 Protein (His Tag) SDS-PAGE
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