-
Product Name
Integrin alpha 6X1A-Specific antibody
- Documents
-
Description
Integrin alpha 6X1A-Specific Rabbit Polyclonal antibody. Positive WB detected in mouse spleen tissue, mouse colon tissue. Observed molecular weight by Western-blot: 100 kDa, 150 kDa
-
Tested applications
ELISA, WB
-
Species reactivity
Human, Mouse; other species not tested.
-
Alternative names
ITGA6 antibody; CD49f antibody; FLJ18737 antibody; Integrin alpha 6 antibody; ITGA6B antibody
-
Isotype
Rabbit IgG
-
Preparation
This antibody was obtained by immunization of Peptide (Accession Number: NM_000210). Purification method: Antigen affinity purified.
-
Clonality
Polyclonal
-
Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
-
Storage instructions
Store at -20℃. DO NOT ALIQUOT
-
Applications
Recommended Dilution:
WB: 1:200-1:1000
-
Validations
mouse spleen tissue were subjected to SDS PAGE followed by western blot with Catalog No:111855(ITGA6-Specific antibody) at dilution of 1:300
-
Background
ITGA6, also named as CD49f and VLA-6, belongs to the integrin alpha chain family. It is a receptor for laminin on platelets. ITGA6 is a receptor for laminin in epithelial cells and it plays a critical structural role in the hemidesmosome. Defects in ITGA6 are a cause of epidermolysis bullosa letalis with pyloric atresia (EB-PA) which also known as junctional epidermolysis bullosa with pyloric atresia (PA-JEB) or aplasia cutis congenita with gastrointestinal atresia. The antibody is specific to isoform Alpha-6X1A, isoform Alpha-6X2A, isoform Alpha-6X1X2A isoform7 and isoform9 of ITGA6.
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"