ID3 antibody

ID3 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

ID3 Rabbit Polyclonal antibody. Positive WB detected in Transfected HEK-293 cells.

ELISA, WB

Human,Mouse,Rat; other species not tested.

1R21 antibody; bHLHb25 antibody; HEIR 1 antibody; HEIR1 antibody; ID3 antibody; Inhibitor of DNA binding 3 antibody

Rabbit IgG

This antibody was obtained by immunization of ID3 recombinant protein (Accession Number: NM_002167). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

The helix-loop-helix (HLH) family of transcription factors plays a central role in the regulation of cell growth, differentiation and tumourigenesis. Members of the Id (inhibitor of DNA binding) class of these nuclear proteins are able to heterodimerise with and thereby antagonise the functions of other transcription factors of this family. Inhibitor of DNA binding 3, dominant negative helix-loop-helix protein (ID3, synonym: HEIR-1) is a member of the ID family of HLH proteins, which lacks a basic DNA-binding domain and inhibits transcription through formation of nonfunctional dimers that are incapable of binding to DNA.

• Woo GH, Takahashi M, Inoue K. Cellular distributions of molecules with altered expression specific to thyroid proliferative lesions developing in a rat thyroid carcinogenesis model. Cancer science. 100(4):617-25. 2009.