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Product Name
Human MGMT (His tag) recombinant protein
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Description
MGMT belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. MGMT involved in the cellular defense against the biological effects of O6-methylguanine in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. MGMT catalyzes the chemical reaction: DNA (containing 6-O-methylguanine) and proteinL-cysteine into DNA (without 6-O-methylguanine) and protein S-methyl-L-cysteine.
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Protein name
O-6-methylguanine-DNA methyltransferase(MGMT)
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Uniprot ID
P16455
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the Human MGMT Met1-Asn207 is expressed with a 6His tag at the N-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human MGMT (His tag) recombinant protein
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