-
Product Name
Human METAP1/KIAA0094 recombinant protein
- Documents
-
Description
Methionine Aminopeptidase 1 is a member of the M24 family of metalloproteases. METAP1 plays an important role in G(2)/M phase regulation of the cell cycle and may serve as a promising target for the discovery and development of new anticancer agents. METAP1 and METAP2 have different substrate specificity due to the differences in both size and shape of the active sites. The proteolytic removal of N-terminal methionine from nascent peptides is catalyzed by a family of enzymes known as methionine aminopeptidases (MetAPs) and is essential for cell growth. Inhibition of METAPs provides a novel strategy in developing anti-cancer drugs.
-
Protein name
methionyl aminopeptidase 1(METAP1)
-
Protein short names
KIAA0094
-
Uniprot ID
P53582
-
Source/Expression Host
E.coli
-
Expression Plasmid/cDNA
A DNA sequence encoding the Human METAP1/KIAA0094 Met1-Phe386 is expressed.
-
Protein Species
Human
-
Purity
>95% as determined by SDS-PAGE.
-
Validations
Human METAP1/KIAA0094 recombinant protein
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"