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Product Name
Human CISD2 Recombinant protein (GST tag)
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Description
Regulator of autophagy that contributes to antagonize BECN1-mediated cellular autophagy at the endoplasmic reticulum. Participates in the interaction of BCL2 with BECN1 and is required for BCL2-mediated depression of endoplasmic reticulum Ca(2+) stores during autophagy. Contributes to BIK-initiated autophagy, while it is not involved in BIK-dependent activation of caspases. Involved in life span control, probably via its function as regulator of autophagy. {PubMed:17846994, PubMed:20010695}.
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Protein name
CDGSH iron-sulfur domain-containing protein 2
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Protein short names
CDGSH2; ERIS; ZCD2
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Uniprot ID
Q8N5K1
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Gene Name
CISD2; CDGSH2; ERIS; ZCD2
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human CISD2 (NP_001008389.1) 61-135 aa was fused with the N-terminal GST tag
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Protein Species
Human
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Activity
Not tested.
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Validations
Recombinant human CISD2 SDS-PAGE
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