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Product Name
GBP2 antibody
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Description
GBP2 Rabbit Polyclonal antibody. Positive IHC detected in human tonsillitis tissue, human pancreas cancer tissue, human spleen tissue. Positive WB detected in human lung tissue, human placenta tissue, K-562 cells, PC-3 cells, rat spleen tissue. Observed molecular weight by Western-blot: 67 kDa
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
GBP 2 antibody; GBP2 antibody; GTP binding protein 2 antibody; HuGBP 2 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of GBP2 recombinant protein (Accession Number: BC022272). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:1000-1:10000
IHC: 1:20-1:200
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Validations
human lung tissue were subjected to SDS PAGE followed by western blot with Catalog No:110892(GBP2 antibody) at dilution of 1:400
Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using Catalog No:110892(GBP2 Antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using Catalog No:110892(GBP2 Antibody) at dilution of 1:50 (under 40x lens)
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Background
GBP2 represents guanylate binding protein 2, interferon-inducible
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References
- Meunier E, Dick MS, Dreier RF. Caspase-11 activation requires lysis of pathogen-containing vacuoles by IFN-induced GTPases. Nature. 509(7500):366-70. 2014.
- Man SM, Karki R, Malireddi RK. The transcription factor IRF1 and guanylate-binding proteins target activation of the AIM2 inflammasome by Francisella infection. Nature immunology. 16(5):467-75. 2015.
- Ohshima J, Sasai M, Liu J. RabGDIα is a negative regulator of interferon-γ-inducible GTPase-dependent cell-autonomous immunity to Toxoplasma gondii. Proceedings of the National Academy of Sciences of the United States of America. 112(33):E4581-90. 2015.
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