CISD2-Specific antibody

CISD2-Specific antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

CISD2-Specific Mouse Monoclonal antibody. Positive IHC detected in human kidney tissue, human testis tissue. Positive WB detected in MCF7 cells, human brain tissue. Observed molecular weight by Western-blot: 15 kDa

ELISA, WB, IHC

Human; other species not tested.

CDGSH iron sulfur domain 2 antibody; CDGSH2 antibody; CISD2 antibody; CISD2-Specific antibody; ERIS antibody; Miner1 antibody; MitoNEET related 1 protein antibody; NAF 1 antibody; WFS2 antibody; ZCD2 antibody

Mouse IgG2b

This antibody was obtained by immunization of recombinant protein (Accession Number: NM_001008388). Purification method: Protein A purified.

Monoclonal

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

CISD2 gene encodes a 15 kDa CDGSH iron-sulfur domain-containing protein 2, which is also named Miner1 or NAF-1, this protein was reported on endoplasmic reticulum membrane or mitochondrion outer membrane. Defects in CISD2 are the cause of Wolfram syndrome type 2 (WFS2), a rare disorder characterized by juvenile-onset insulin-dependent diabetes mellitus with optic atrophy. CISD2 regulates autophagy program by interacting BCL2, contributing to antagonize BECN1-mediated cellular autophagy at the endoplasmic reticulum. This monoclonal antibody is specific to CISD2 and does not cross-react with CISD1.