CASK antibody

CASK antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

CASK Rabbit Polyclonal antibody. Positive WB detected in mouse kidney tissue, mouse brain tissue, mouse liver tissue. Observed molecular weight by Western-blot: 100-110kd,50-55kd

ELISA, WB

human, mouse, rat; other species not tested.

CASK antibody; CAGH39 antibody; FLJ31914 antibody; FLJ22219 antibody; FGS4 antibody

Rabbit IgG

This antibody was obtained by immunization of Peptide (Accession Number: NM_003688). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

CASK, also named as LIN2, belongs to the MAGUK family. It is a multidomain scaffolding protein with a role in synaptic transmembrane protein anchoring and ion channel trafficking. It contributes to neural development and regulation of gene expression via interaction with the transcription factor TRB1. CASK binds to cell-surface proteins, including amyloid precursor protein, neurexins and syndecans. It may mediate a link between the extracellular matrix and the actin cytoskeleton via its interaction with syndecan and with the actin/spectrin-binding protein 4.1. Defects in CASK are the cause of mental retardation X-linked CASK-related (MRXCASK) . Defects in CASK are the cause of FG syndrome type 4 (FGS4). This antibody can recognize all the isoform of CASK.