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Product Name
Human BVES / POPDC1 (GST Tag) recombinant protein
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Description
Cell adhesion molecule involved in the establishment and/or maintenance of cell integrity. Involved in the formation and regulation of the tight junction (TJ) paracellular permeability barrier in epithelial cells. Plays a role in VAMP3-mediated vesicular transport and recycling of different receptor molecules through its interaction with VAMP3. Plays a role in the regulation of cell shape and movement by modulating the Rho-family GTPase activity through its interaction with ARHGEF25/GEFT. Induces primordial adhesive contact and aggregation of epithelial cells in a Ca(2+)-independent manner. Also involved in striated muscle regeneration and repair and in the regulation of cell spreading.
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Protein name
Blood vessel epicardial substance
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Protein short names
POP1; HBVES; POPEYE DOMAIN CONTAINING 1; BLOOD VESSEL EPICARDIAL SUBSTANCE; RP3-522O2.1; POPEYE DOMAIN-CONTAINING PROTEIN 1; POPEYE 1; BVES; POPDC1; POPEYE PROTEIN 1; MBVES
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Uniprot ID
Q8NE79
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Gene Name
BVES; POP1; POPDC1
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human BVES (NP_671488.1) (Met1-Asn36) was fused with the GST tag at the N-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human BVES/GST chimera consists of 267 amino acids and has a predicted molecular mass of 30.8 kDa. It migrates as an approximately 32.2 KDa band in SDS-PAGE under reducing conditions.
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Purity
> 90 % as determined by SDS-PAGE
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Validations
Human BVES / POPDC1 Protein (GST Tag) SDS-PAGE
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