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Product Name
BVES antibody
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Description
BVES Rabbit Polyclonal antibody. Positive WB detected in mouse skeletal muscle tissue. Positive IHC detected in human ovary tumor tissue. Observed molecular weight by Western-blot: 41-70 kDa
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Tested applications
ELISA, IHC, WB
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
BVES antibody; HBVES antibody; POP1 antibody; POPDC1 antibody; Popeye protein 1 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of BVES recombinant protein (Accession Number: NM_001199563). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IHC: 1:20-1:200
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Validations
mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with Catalog No:108556(BVES antibody) at dilution of 1:500
Immunohistochemical of paraffin-embedded human ovary tumor using Catalog No:108556(BVES antibody) at dilution of 1:100 (under 10x lens)
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Background
BVES, also named as POP1, POPDC1 and hBVES, belongs to the popeye family. It is cell adhesion molecule involved in the establishment and/or maintenance of cell integrity. It is involved in the formation and regulation of the tight junction (TJ) paracellular permeability barrier in epithelial cells. It is also involved in striated muscle regeneration and repair and in the regulation of cell spreading. BVES is expressed in the progenitors of coronary artery smooth muscle cells as well as in differentiated smooth muscle cells.
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References
- Luo D, Huang H, Lu ML. Abnormal expression of adhesion protein Bves is associated with gastric cancer progression and poor survival. Pathology oncology research : POR. 18(2):491-7. 2012.
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