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Product Name
ARHGDIB antibody
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Description
ARHGDIB Mouse Monoclonal antibody. Positive WB detected in U937 cells. Observed molecular weight by Western-blot: 27 kDa
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Tested applications
ELISA, WB
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Species reactivity
Human; other species not tested.
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Alternative names
ARHGDIB antibody; GDIA2 antibody; GDID4 antibody; Ly GDI antibody; LYGDI antibody; RAP1GN1 antibody; Rho GDI 2 antibody; Rho GDI beta antibody; RhoGDI2 antibody
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Isotype
Mouse IgG2b
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Preparation
This antibody was obtained by immunization of ARHGDIB recombinant protein (Accession Number: NM_001321423). Purification method: Protein A purified.
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Clonality
Monoclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
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Validations
U-937 cells were subjected to SDS PAGE followed by western blot with Catalog No:107067(ARHGDIB antibody) at dilution of 1:1000
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Background
ARHGDIB, also known as RhoGDI2, is a conserved member of the RhoGDI family and plays an important role in cell migrations. It regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. It is mainly in hematopoietic, endothelial, and epithelial cells. It has been linked to tumorigenesis and metastasis. RhoGDI2 expression is downregulated in several cancer types, such as bladder, lung and lymphoma, but is upregulated in prostate and gastric cancer.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"