Anti-YB1 Rabbit antibody

Cat.#: 167808

Size:

Special Price 247.7 USD

Availability: In Stock
- +

Add to cart to get an online quotation

Product Information

  • Product Name
    Anti-YB1 Rabbit antibody
  • Documents
  • Description
    YB1 Rabbit monoclonal antibody
  • Tested applications
    WB, IHC-P, ICC/IF, FC, IP
  • Species reactivity
    Human, Mouse
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: A synthetic peptide of human YB1
  • Clonality
    Monoclonal
  • Formulation
    50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA
  • Storage instructions
    Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Applications

    WB: 1/1000

    IHC: 1/500

    ICC/IF: 1/20

    FC: 1/50

    IP: 1/20

  • Validations

    Western blot detection of YB1 in Hela,C2C12 cell lysates using YB1 Rabbit mAb(1:1000 diluted).Predicted band size:36kDa.Observed band size:49kDa.

    Western blot detection of YB1 in Hela,C2C12 cell lysates using YB1 Rabbit mAb(1:1000 diluted).Predicted band size:36kDa.Observed band size:49kDa.

  • Background
    This gene encodes a highly conserved cold shock domain protein that has broad nucleic acid binding properties. The encoded protein functions as both a DNA and RNA binding protein and has been implicated in numerous cellular processes including regulation of transcription and translation, pre-mRNA splicing, DNA reparation and mRNA packaging. This protein is also a component of messenger ribonucleoprotein (mRNP) complexes and may have a role in microRNA processing. This protein can be secreted through non-classical pathways and functions as an extracellular mitogen. Aberrant expression of the gene is associated with cancer proliferation in numerous tissues. This gene may be a prognostic marker for poor outcome and drug resistance in certain cancers. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on multiple chromosomes. [provided by RefSeq, Sep 2015]

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"