-
Product Name
Anti-LXR alpha Rabbit antibody
- Documents
-
Description
LXR alpha Rabbit polyclonal antibody
-
Tested applications
WB, ICC/IF, FC
-
Species reactivity
Human, Mouse, Rat
-
Isotype
Rabbit IgG
-
Preparation
Antigen: A synthesized peptide derived from human LXR alpha
-
Clonality
Polyclonal
-
Formulation
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
-
Storage instructions
Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
-
Applications
WB: 1/500-1/2000
ICC/IF: 1/50-1/200
FC: 1/50
-
Validations
Western blot analysis of LXR alpha expression in Jurkat cell lysate.
-
Background
Swiss-Prot Acc.Q13133.Orphan receptor. Interaction with RXR shifts RXR from its role as a silent DNA-binding partner to an active ligand-binding subunit in mediating retinoid responses through target genes defined by LXRES. LXRES are DR4-type response elements characterized by direct repeats of two similar hexanuclotide half-sites spaced by four nucleotides. Plays an important role in the regulation of cholesterol homeostasis, regulating cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8.
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"