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Product Name
Anti-Insulin Receptor Rabbit antibody
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Description
Insulin Receptor Rabbit polyclonal antibody
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Tested applications
WB, ICC/IF
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Species reactivity
Human, Rat
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthesized peptide derived from human Insulin Receptor
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Clonality
Polyclonal
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Formulation
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage instructions
Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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Applications
WB: 1/1000-1/2000
ICC/IF: 1/50-1/200
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Validations
Western blot analysis of Insulin Receptor expression in HeLa cell lysate.
Immunofluorescent analysis of BxPC-3 cells, using Insulin Receptor Antibody.
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Background
Swiss-Prot Acc.P06213.Insulin Receptor is a transmembrane receptor tyrosine kinase that is widely expressed in many cell lines and cell types within fetal and postnatal tissues; Insulin binding to IR induces phosphorylation of intracellular tyrosine kinase domains and recruitment of multiple SH2 and SH3 domain-containing intracellular proteins that serve as signaling intermediates for pleiotropic effects of insulin.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"