Anti-FADD Rabbit antibody

Cat.#: 168656

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Special Price 441.3 USD

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Product Information

  • Product Name
    Anti-FADD Rabbit antibody
  • Documents
  • Description
    FADD Rabbit monoclonal antibody
  • Tested applications
    WB, FC, IP
  • Species reactivity
    Mouse, Rat
  • Alternative names
    GIG3; MORT1 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: A synthetic peptide of human FADD
  • Clonality
    Monoclonal
  • Formulation
    Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
  • Storage instructions
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze / thaw cycle.
  • Applications

    WB: 1/1000

  • Validations

    Western blot detection of FADD in Rat Brain,3T3 cell lysates using FADD Rabbit mAb(1:1000 diluted).Predicted band size:23kDa.Observed band size:28kDa.

    Western blot detection of FADD in Rat Brain,3T3 cell lysates using FADD Rabbit mAb(1:1000 diluted).Predicted band size:23kDa.Observed band size:28kDa.

  • Background
    Swiss-Prot Acc.Q13158.Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"