Anti-ERCC1 (7F6) Mouse antibody

Anti-ERCC1 (7F6) Mouse antibody

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ERCC1 (7F6) Mouse monoclonal antibody

WB

Human

COFS 4;COFS4;DNA excision repair protein ERCC 1;DNA excision repair protein ERCC-1;DNA excision repair protein ERCC1;ERCC 1;ERCC1;ERCC1_HUMAN;Excision repair cross complementing 1;Excision Repair Cross Complementing Rodent Repair Deficiency Complementatio antibody

Mouse IgG2b

Antigen: Purified recombinant human ERCC1 protein fragments expressed in E.coli.

Monoclonal

Purified mouse monoclonal antibody in PBS(pH 7.4) containing with 0.02% sodium azide 0.1mg/mlBSA and 50% glycerol.

Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

Swiss-Prot Acc.P07992.Isoform 1:Non-catalytic component of a structure-specific DNA repair endonuclease responsible for the 5'-incision during DNA repair.Responsible,in conjunction with SLX4,for the first step in the repair of interstrand cross-links (ICL).Participates in the processing of anaphase bridge-generating DNA structures,which consist in incompletely processed DNA lesions arising during S or G2 phase,and can result in cytokinesis failure.Also required for homology-directed repair (HDR) of DNA double-strand breaks,in conjunction with SLX4.