LOCUS       V005527                11424 bp    DNA     circular SYN 18-DEC-2018
DEFINITION  Exported.
ACCESSION   V005527
VERSION     V005527
KEYWORDS    .
SOURCE      synthetic DNA construct
  ORGANISM  synthetic DNA construct
            .
REFERENCE   1  (bases 1 to 11424)
  AUTHORS   Windbichler N, Menichelli M, Papathanos PA, Thyme SB, Li H, Ulge UY,
            Hovde BT, Baker D, Monnat RJ Jr., Burt A, Crisanti A.
  TITLE     A synthetic homing endonuclease-based gene drive system in the human
            malaria mosquito
  JOURNAL   Nature 473 (7346), 212-215 (2011)
   PUBMED   21508956
REFERENCE   2  (bases 1 to 11424)
  AUTHORS   Windbichler N.
  TITLE     Homing
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 11424)
  AUTHORS   Windbichler N.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-AUG-2010) Imperial College London, Imperial College
            Road, London SW7 2AZ, England
REFERENCE   4  (bases 1 to 11424)
  TITLE     Direct Submission
REFERENCE   5  (bases 1 to 11424)
  AUTHORS   .
  TITLE     Direct Submission
COMMENT     SGRef: number: 1; type: "Journal Article"; journalName: "Nature";
            date: "2011"; volume: "473"; issue: "7346"; pages: "212-215"
            SGRef: number: 2; type: "Journal Article"; journalName:
            "Unpublished"
            SGRef: number: 3; type: "Journal Article"; journalName: "Submitted
            (18-AUG-2010) Imperial College London, Imperial College Road, London
            SW7 2AZ, England"
            SGRef: number: 4; type: "Journal Article"
FEATURES             Location/Qualifiers
     source          1..11424
                     /mol_type="other DNA"
                     /organism="synthetic DNA construct"
     regulatory      complement(18..440)
                     /gene="beta-2-tubulin"
                     /regulatory_class="terminator"
     gene            complement(18..440)
                     /gene="beta-2-tubulin"
                     /label="beta-2-tubulin"
     CDS             complement(459..1163)
                     /gene="SCEI"
                     /label="Intron-encoded endonuclease I-SceI"
                     /note="Intron-encoded endonuclease I-SceI from
                     Saccharomyces cerevisiae (strain ATCC 204508 / S288c).
                     Accession#: P03882"
     CDS             complement(1167..1193)
                     /label="HA"
                     /note="HA (human influenza hemagglutinin) epitope tag"
     CDS             complement(1212..1232)
                     /label="SV40 NLS"
                     /note="nuclear localization signal of SV40 (simian virus
                     40) large T antigen"
     regulatory      complement(1289..1880)
                     /gene="beta-2-tubulin"
                     /regulatory_class="promoter"
     gene            complement(1289..1880)
                     /gene="beta-2-tubulin"
                     /label="beta-2-tubulin"
     CDS             1903..2619
                     /label="EGFP"
                     /note="enhanced GFP"
     polyA_signal    2741..2862
                     /label="SV40 poly(A) signal"
                     /note="SV40 polyadenylation signal"
     promoter        2930..5507
                     /label="Ac5 promoter"
                     /note="Drosophila melanogaster actin 5C promoter"
     CDS             5519..6196
                     /label="DsRed1"
                     /note="wild-type DsRed"
     polyA_signal    6367..6797
                     /label="hsp70 poly(A)"
                     /note="polyadenlyation signal from the Drosophila
                     melanogaster hsp70Ab gene"
     protein_bind    complement(7917..7986)
                     /label="attB"
                     /note="attB site for the phi-C31 integrase (Groth et al.,
                     2000)"
     primer_bind     complement(8022..8038)
                     /label="M13 rev"
                     /note="common sequencing primer, one of multiple similar
                     variants"
     protein_bind    8046..8062
                     /label="lac operator"
                     /bound_moiety="lac repressor encoded by lacI"
                     /note="The lac repressor binds to the lac operator to
                     inhibit transcription in E. coli. This inhibition can be
                     relieved by adding lactose or
                     isopropyl-beta-D-thiogalactopyranoside (IPTG)."
     promoter        complement(8070..8100)
                     /label="lac promoter"
                     /note="promoter for the E. coli lac operon"
     protein_bind    complement(8115..8136)
                     /label="CAP binding site"
                     /note="CAP binding activates transcription in the presence
                     of cAMP."
     rep_origin      complement(8424..9012)
                     /direction=LEFT
                     /label="ori"
                     /note="high-copy-number ColE1/pMB1/pBR322/pUC origin of
                     replication"
     CDS             complement(9186..10043)
                     /label="AmpR"
                     /note="beta-lactamase"
     promoter        complement(10044..10148)
                     /label="AmpR promoter"
     regulatory      11124..11385
                     /gene="3xP3"
                     /regulatory_class="promoter"
     gene            11124..11385
                     /gene="3xP3"
                     /label="3xP3"
ORIGIN
        1 tagggataag cggccgcggc attgacctgg gaatcgcaat ttgttcgggt aacagaatca
       61 gaattgactc cagaattgga attagctcca gaatggggat caattcttga attaaatacg
      121 aagtttcaga agcgaaatca ctctgggaat ctccatgaga attttgagcc aattctgatc
      181 ccggaatcaa ttccggaacc aattccggag ccgattccgg aaactaatac cgaacctact
      241 atccggaaac gattccagaa aacttcggag ctacttccca tcactgcact aatccttaca
      301 catgagtacg aagcaaaaac tgagaaatgg caacaaaaac gaagcgaata gagtggaaaa
      361 aaacattttt attgacccca acaccgctgc ttagcagaaa ttttacacat aatttagggt
      421 gttcaattta gctttagtta ctcgaggtcg acttattatt tcaggaaagt ttcggaggag
      481 atagtgttcg gcagtttgta catcatctgc gggatcaggt acggtttgat caggttgtag
      541 aagatcaggt aagacataga atcgatgtag atgatcggtt tgtttttgtt gatttttacg
      601 taacagttca gttggaattt gttacgcaga cccttaacca ggtattctac ttcttcgaaa
      661 gtgaaagact gggtgttcag tacgatcgat ttgttggtag agtttttgtt gtaatcccat
      721 ttaccaccat catccatgaa ccagtatgcc agagacatcg gggtcaggta gttttcaacc
      781 aggttgttcg ggatggtttt tttgttgtta acgatgaaca ggttagccag tttgttgaaa
      841 gcttggtgtt tgaaagtctg ggcgccccag gtgattacca ggttacccag gtggttaaca
      901 cgttcttttt tgtgcggcgg ggacagtacc cactgatcgt acagcagaca tacgtggtcc
      961 atgtatgctt tgtttttcca ctcgaactgc atacagtagg ttttaccttc atcacgagaa
     1021 cggatgtaag catcacccag gatcagaccg atacctgctt cgaactgttc gatgttcagt
     1081 tcgatcagct gggatttgta ttctttcagc agtttagagt tcggacccag gttcattacc
     1141 tggttttttt tgatgttttt catacccgca tagtcaggaa catcgtatgg gtacataaat
     1201 cgtgggtctt ctacttttcg tttttttttt ggtggtgctg catgctgcgc atcggccgta
     1261 gcttcgtcgt ctgatgatga tcccatggtt tcgaaactgt gaaactgtga aagccgtttg
     1321 atatttagcg gattttggaa cgcacgagcg ttgctctcta agcgctggga atacttacgg
     1381 aaggacctct atcggccgaa tacgcgattc ctactgggta cacaaatttc tagtttaagc
     1441 cgtttttttc ttttgtccct aatggaacaa ctttgtgaat ggactaacta cacagtttct
     1501 atcaatctgt cgaccaacgt ctctgaaggt tctgcacgaa atgatccggc acgtacggct
     1561 catatgacta ctatgatcat cttttgctgg ttcggccgat tgcgatgcca caaataaatt
     1621 cgtatgtctt cttggatggg atgatgcatc cactttcctc catattatgt agcataagtt
     1681 cttgcaatta atatgtgtgt agagttgttc aattcgtaat tatggataaa aaaaaaataa
     1741 aaaactgtca tgtcatttac aaaactatat caattatgaa cgctagaata atttttttcc
     1801 ataaccattt tttaatcagt tttatttttt ttctcaacgt agtccacaaa gcatcaaaga
     1861 gcacatcgaa caatttcatg gcggccgcat aacagggtaa tcatggtgag caagggcgag
     1921 gagctgttca ccggggtggt gcccatcctg gtcgagctgg acggcgacgt aaacggccac
     1981 aagttcagcg tgtccggcga gggcgagggc gatgccacct acggcaagct gaccctgaag
     2041 ttcatctgca ccaccggcaa gctgcccgtg ccctggccca ccctcgtgac caccctgacc
     2101 tacggcgtgc agtgcttcag ccgctacccc gaccacatga agcagcacga cttcttcaag
     2161 tccgccatgc ccgaaggcta cgtccaggag cgcaccatct tcttcaagga cgacggcaac
     2221 tacaagaccc gcgccgaggt gaagttcgag ggcgacaccc tggtgaaccg catcgagctg
     2281 aagggcatcg acttcaagga ggacggcaac atcctggggc acaagctgga gtacaactac
     2341 aacagccaca acgtctatat catggccgac aagcagaaga acggcatcaa ggtgaacttc
     2401 aagatccgcc acaacatcga ggacggcagc gtgcagctcg ccgaccacta ccagcagaac
     2461 acccccatcg gcgacggccc cgtgctgctg cccgacaacc actacctgag cacccagtcc
     2521 gccctgagca aagaccccaa cgagaagcgc gatcacatgg tcctgctgga gttcgtgacc
     2581 gccgccggga tcactctcgg catggacgag ctgtacaagt aaagcgcgac tctagatcat
     2641 aatcagccat accacatttg tagaggtttt acttgcttta aaaaacctcc cacacctccc
     2701 cctgaacctg aaacataaaa tgaatgcaat tgttgttgtt aacttgttta ttgcagctta
     2761 taatggttac aaataaagca atagcatcac aaatttcaca aataaagcat ttttttcact
     2821 gcattctagt tgtggtttgt ccaaactcat caatgtatct taaagcttat cgatacgcgt
     2881 acggcgcgcc taggccggcc gaattcaaat gatacttcta aaaaaaaatc atgaatggca
     2941 tcaactctga atcaaatctt tgcagatgca cctacttctc atttccactg tcacatcatt
     3001 tttccagatc tcgctgcctg ttatgtggcc cacaaaccaa gacacgtttt atggccatta
     3061 aagctggctg atcgtcgcca aacaccaaat acataatgaa tatgtacaca ttcgagaaag
     3121 aagcgatcaa agaagcgtct tcgggcggag taggagaatg cggaggagaa ggagaacgag
     3181 ctgatctagt atctctccac aatccaatgc caactgacca actggccata ttcggagcaa
     3241 tttgaagcca atttccatcg cctggcgatc gctccattct tggctatatg tttttcaccg
     3301 ttacccgggg ccattttcaa agactcgtcg gcaagataag attgtgtcac tcgctgtctc
     3361 tcttcatttg tcgaagaatg ctgaggaatt tcgcgatgac gtcggcgagt attttgaaga
     3421 atgagaataa tttgtattta tacgaaaatc agttagtgga attttctaca aaaacatgtt
     3481 atctatagat aattttgttg caaaatatgt tgactatgac aaagaactgg aattaagtgg
     3541 catattttgc attgctttcc gataatagtt gtatttttat aaagtaaagc gtttgtaaaa
     3601 taaatacctt taatgtattc tcattttctt atgtatttat aatggcaatg atgatactga
     3661 tgatatttta agatgatgcc agaccaaaag gcttgaattt ctgcgtcttt tgccgaacgc
     3721 agtgcatgtg caattgttgt tttttggaat attcaatttt cggactgtcc gctttgattt
     3781 cagtttcttg gcttattcaa aaagcaaagt aaagccaaaa aagcgagatg gcaataccaa
     3841 atgcggcaaa acggtagtgg aaggaaaggg gtgcggggca gcggaaggaa gggtggggcg
     3901 gggcgtggcg gggtctgtgg ctgggcgcga cgtcaccgac gttggagcca ctcctttgac
     3961 catgtgtgcg tgtgtgtatt attcgtgtct cgccactcgc cggttgtttt tttcttttta
     4021 tgctgcgctc tctctagcgc catctcgctt acgcatgctc aacgcaccgc atgttgccgt
     4081 ttccttttat gcgtcatttt ggctcgaaat aggcaattat ttaaacaaag attagtcaac
     4141 gaaaacgcta aaataaataa gtctacaata tggttactta ttgccatgtg tgtgcagcca
     4201 acgatagcaa caaaagcaac aacacaggtg gctttccctc tttcactttt tgtttgcaag
     4261 ccgcgtgcga gcaagacggc acgaccggca aacgcaatta cgctgacaaa gagcagacga
     4321 agttttggcg aaaaacatca aggcgcctga tacgaatgca tttgcaataa caattgcgat
     4381 atttaatatt gtttatgaag ctgtttgact tcaaaacaca caaaaaaaaa aataaaacaa
     4441 attatttgaa agagaattag gaatcggacg cttatcgtta gggtaacaac aagaaatgct
     4501 tactgagtca cagcctctgg aaaactgccg caagccagag agagagagaa aaagagggag
     4561 agcagcttag accgcatgtg cttgtgtgtg aggcgtctct ctcttcgtct ctgttgcgca
     4621 aacgcataga ctgcactgaa aaaatcgatt acctattttt tatgaatgaa tatttgcact
     4681 attactattc aaaactatta agatagcaat cacattcaat agccaaatac tataccacct
     4741 gagcgatgca acgaaatgat caatttgagc aaaaatgctg catatttagg acggcatcat
     4801 tatagaaatg cttcttgctg tgtacttttc tctcgtctgg cagctgtttc gccgttattg
     4861 ttaaaaccgg cttaagttag gtgtgttttc tacgactagt gaatgcccta ctagaagatg
     4921 tgtgttgcac aaaatgtccc tggaataacc aatttgaagt gcagatagca gtaaacgtaa
     4981 gctaatatga atattattta actgtaatgt tttaatatcg ctggacatta ctaataaacc
     5041 cactataaac acatgtacat atgtatgttt tggcatacaa tgagtagttg gggaaaaaat
     5101 gtgtaaaagc accgtgacca tcacagcata aagataacca gctgaagtat cgaatatgag
     5161 taacccccaa attgaatcac atgccgcaac tgataggacc catggaagta cactcttcat
     5221 ggcgatatac aagacacaca caagcacgaa cacccagttg cggaggaaat tctccgtaaa
     5281 tgaaaaccca atcggcgaac aattcatacc catatatggt aaaagttttg aacgcgactt
     5341 gagagcggag agcattgcgg ctgataaggt tttagcgcta agcgggcttt ataaaacggg
     5401 ctgcgggacc agttttcata tcactaccgt ttgagttctt gtgctgtgtg gatactcctc
     5461 ccgacacaaa gccgctccat cagccagcag tcgtctaatc cagagacccc ggatccccat
     5521 ggtgcgctcc tccaagaacg tcatcaagga gttcatgcgc ttcaaggtgc gcatggaggg
     5581 caccgtgaac ggccacgagt tcgagatcga gggcgagggc gagggccgcc cctacgaggg
     5641 ccacaacacc gtgaagctga aggtgaccaa gggcggcccc ctgcccttcg cctgggacat
     5701 cctgtccccc cagttccagt acggctccaa ggtgtacgtg aagcaccccg ccgacatccc
     5761 cgactacaag aagctgtcct tccccgaggg cttcaagtgg gagcgcgtga tgaacttcga
     5821 ggacggcggc gtggtgaccg tgacccaaga ctcctccctg caggacggct gcttcatcta
     5881 caaggtgaag ttcatcggcg tgaacttccc ctccgacggc cccgtaatgc agaagaagac
     5941 catgggctgg gaggcctcca ccgagcgcct gtacccccgc gacggcgtgc tgaagggcga
     6001 gatccacaag gccctgaagc tgaaggacgg cggccactac ctggtggagt tcaagtccat
     6061 ctacatggcc aagaagcccg tgcagctgcc cggctactac tacgtggact ccaagctgga
     6121 catcacctcc cacaacgagg actacaccat cgtggagcag tacgagcgca ccgagggccg
     6181 ccaccacctg ttcctgtagt ctagatgtac gaacacgcat ttatcatata ataaatcgat
     6241 aactttggca aaaaaaaaaa aaaaaaaaaa aaaanctcgn gggggggccc gctagagatc
     6301 ttccatacct accagttctg cgcctgcagc aatggcaaca acgttgcccg gatcgaggtc
     6361 gactaaggcc aaagagtcta atttttgttc atcaatgggt tataacatat gggttatatt
     6421 ataagtttgt tttaagtttt tgagactgat aagaatgttt cgatcgaata ttccatagaa
     6481 caacaatagt attacctaat taccaagtct taatttagca aaaatgttat tgcttataga
     6541 aaaaataaaa tnatttattt gaaatttaaa gtcaacttgt catttaatgt cttgtagact
     6601 tttgaaagtc ttacgataca attagtatct aatatacatg ggttcattct acattctata
     6661 ttagtgatga tttctttagc tagtaataca ttttaattat attcggcttt gatgattttc
     6721 tgattttttc cgaacggatt ttcgtagacc ctttcgatct cataatggct cattttattg
     6781 cgatggacgg tcaggagagc tccacttttg aatttctgtt cgcagacacc gcatttgtag
     6841 cacatagccg ggacatccgg tttggggaga ttttccagtc tctgttgcaa ttggttttcg
     6901 ggaatgcgtt gcaggcgcat acgctctata tcctccgaac ggcgctggtt gaccctagca
     6961 tttacataag gatcagcagc aaaatttgcc tctacttcat tgcccggaat cacagcaatc
     7021 agatgtccct ttcggttacg atggatattc aggtgcgaac cgcacacaaa gctctcgccg
     7081 cacactccac actgatatgg tcgctcgccc gtgtggcggc cgcctgcagc tggcgccatc
     7141 gatacgcgta cgtcgcgacc gcggacatgt acagagctcg agaagtacta gtggccacgt
     7201 gggccgtgca ccttaagctt ggcgcgccta ggccggccgc tagcagatct catcgctttg
     7261 cagaagagca gagaggatat gctcatcgtc taaagaacta cccattttat tatatattag
     7321 tcacgatatc tataacaaga aaatatatat ataataagtt atcacgtaag tagaacatga
     7381 aataacaata taattatcgt atgagttaaa tcttaaaagt cacgtaaaag ataatcatgc
     7441 gtcattttga ctcacgcggt cgttatagtt caaaatcagt gacacttacc gcattgacaa
     7501 gcacgcctca cgggagctcc aagcggcgac tgagatgtcc taaatgcaca gcgacggatt
     7561 cgcgctattt agaaagagag agcaatattt caagaatgca tgcgtcaatt ttacgcagac
     7621 tatctttcta gggttaaaaa agatttgcgc tttactcgac ctaaacttta aacacgtcat
     7681 agaatcttcg tttgacaaaa accacattgt ggccaagctg tgctcgacat gcccgccgtg
     7741 accgtcgaga acccgctgac gctgccccgc gtatccgcac ccgccgacgc cgtcgcacgt
     7801 cccgtgctca ccgtgaccac cgcgcccagc ggtttcgagg gcgagggctt cccggtgcgc
     7861 cgcgcgttcg ccgggatcaa ctaccgccac ctcgacccgt tcatcatgat ggaccagatg
     7921 ggtgaggtgg agtacgcgcc cggggagccc aagggcacgc cctggcaccc gcaccgcggc
     7981 ttcgagaccg tgacctacat cgtcgaggaa ttcgtaatca tgtcatagct gtttcctgtg
     8041 tgaaattgtt atccgctcac aattccacac aacatacgag ccggaagcat aaagtgtaaa
     8101 gcctggggtg cctaatgagt gagctaactc acattaattg cgttgcgctc actgcccgct
     8161 ttccagtcgg gaaacctgtc gtgccagctg cattaatgaa tcggccaacg cgcggggaga
     8221 ggcggtttgc gtattgggcg ctcttccgct tcctcgctca ctgactcgct gcgctcggtc
     8281 gttcggctgc ggcgagcggt atcagctcac tcaaaggcgg taatacggtt atccacagaa
     8341 tcaggggata acgcaggaaa gaacatgtga gcaaaaggcc agcaaaaggc caggaaccgt
     8401 aaaaaggccg cgttgctggc gtttttccat aggctccgcc cccctgacga gcatcacaaa
     8461 aatcgacgct caagtcagag gtggcgaaac ccgacaggac tataaagata ccagcggttt
     8521 ccccctggaa gctccctcgt gcgctctcct gttccgaccc tgccgcttac cggatacctg
     8581 tccgcctttc tcccttcggg aagcgtggcg ctttctcaat gctcacgctg taggtatctc
     8641 agttcggtgt aggtcgttcg ctccaagctg ggctgtgtgc acgaaccccc cgttcagccc
     8701 gaccgctgcg ccttatccgg taactatcgt cttgagtcca acccggtaag acacgactta
     8761 tcgccactgg cagcagccac tggtaacagg attagcagag cgaggtatgt aggcggtgct
     8821 acagagttct tgaagtggtg gcctaactac ggctacacta gaaggacagt atttggtatc
     8881 tgcgctctgc tgaagccagt taccttcgga aaaagagttg gtagctcttg atccggcaaa
     8941 caaaccaccg ctggtagcgg tggttttttt gtttgcaagc agcagattac gcgcagaaaa
     9001 aaaggatctc aagaagatcc tttgatcttt tctacggggt ctgacgctca gtggaacgaa
     9061 aactcacgtt aagggatttt ggtcatgaga ttatcaaaaa ggatcttcac ctagatcctt
     9121 ttaaattaaa aatgaagttt taaatcaatc taaagtatat atgagtaaac ttggtctgac
     9181 agttaccaat gcttaatcag tgaggcacct atctcagcga tctgtctatt tcgttcatcc
     9241 atagttgcct gactccccgt cgtgtagata actacgatac gggagggctt accatctggc
     9301 cccagtgctg caatgatacc gcgagaccca cgctcaccgg ctccagattt atcagcaata
     9361 aaccagccag ccggaagggc cgagcgcaga agtggtcctg caactttatc cgcctccatc
     9421 cagtctatta attgttgccg ggaagctaga gtaagtagtt cgccagttaa tagtttgcgc
     9481 aacgttgttg ccattgctac aggcatcgtg gtgtcacgct cgtcgtttgg tatggcttca
     9541 ttcagctccg gttcccaacg atcaaggcga gttacatgat cccccatgtt gtgcaaaaaa
     9601 gcggttagct ccttcggtcc tccgatcgtt gtcagaagta agttggccgc agtgttatca
     9661 ctcatggtta tggcagcact gcataattct cttactgtca tgccatccgt aagatgcttt
     9721 tctgtgactg gtgagtactc aaccaagtca ttctgagaat agtgtatgcg gcgaccgagt
     9781 tgctcttgcc cggcgtcaat acgggataat accgcgccac atagcagaac tttaaaagtg
     9841 ctcatcattg gaaaacgttc ttcggggcga aaactctcaa ggatcttacc gctgttgaga
     9901 tccagttcga tgtaacccac tcgtgcaccc aactgatctt cagcatcttt tactttcacc
     9961 agcgtttctg ggtgagcaaa aacaggaagg caaaatgccg caaaaaaggg aataagggcg
    10021 acacggaaat gttgaatact catactcttc ctttttcaat attattgaag catttatcag
    10081 ggttattgtc tcatgagcgg atacatattt gaatgtattt agaaaaataa acaaataggg
    10141 gttccgcgca catttccccg aaaagtgcca cctgacgtct aagaaaccat tattatcatg
    10201 acattaacct ataaaaatag gcgtatcacg aggccctttc gtctcgcgcg tttcggtgat
    10261 gacggtgaaa acctctgaca catgcagctc ccggagacgg tcacagcttg tctgtaagcg
    10321 gatgccggga gcagacaagc ccgtcagggc gcgtcagcgg gtgttggcgg gtgtcggggc
    10381 tggcttaact atgcggcatc agagcagatt gtactgagag tgcaccatat gggtattcac
    10441 gacagcaggc tgaataataa aaaaattaga aactattatt taaccctaga aagataatca
    10501 tattgtgacg tacgttaaag ataatcatgc gtaaaattga cgcatgtgtt ttatcggtct
    10561 gtatatcgag gtttatttat taatttgaat agatattaag ttttattata tttacactta
    10621 catactaata ataaattcaa caaacaattt atttatgttt atttatttat taaaaaaaaa
    10681 caaaaactca aaatttcttc tataaagtaa caaaactttt aaacattctc tcttttacaa
    10741 aaataaactt attttgtact ttaaaaacag tcatgttgta ttataaaata agtaattagc
    10801 ttaacttata cataatagaa acaaattata cttattagtc agtccagaaa caactttggc
    10861 acctgcaggt catcacagaa cacatttggt ctagcgtgtc cactccgcct ttagtttgat
    10921 tataatacat aaccatttgc ggtttaccgg tactttcgtt gatagaagca tcctcatcac
    10981 aagatgataa taagtatacc atcttagctg gcttcggttt atatgagacg agagtaaggg
    11041 gtccgtcaaa acaaaacatc gatgttccca ctggcctgga gcgactgttt ttcagtactt
    11101 ccggtatctc gcgtttgttt gatcgcacgg ttcccacaat ggttaattcg agctcgcccg
    11161 gggatctaat tcaattagag actaattcaa ttagagctaa ttcaattagg atccaagctt
    11221 atcgatttcg aaccctcgac cgccggagta taaatagagg cgcttcgtct acggagcgac
    11281 aattcaattc aaacaagcaa agtgaacacg tcgctaagcg aaagctaagc aaataaacaa
    11341 gcgcagctga acaagctaaa caatcggggt accgctagag tcgacggtac cgcgggcccg
    11401 ggatccaccg gtcgccacca tgcc
//
