LOCUS       40924_2982       12653 bp DNA     circular SYN 17-DEC-2018
DEFINITION  AAVS1 targeting vector pA1.GFP.A2, complete sequence.
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      synthetic DNA construct
  ORGANISM  synthetic DNA construct
REFERENCE   1  (bases 1 to 12653)
  AUTHORS   van Nierop GP, de Vries AA, Holkers M, Vrijsen KR, Goncalves MA.
  TITLE     Stimulation of homology-directed gene targeting at an endogenous 
            human locus by a nicking endonuclease
  JOURNAL   Nucleic Acids Res. 37 (17), 5725-5736 (2009)
  PUBMED    19651880
REFERENCE   2  (bases 1 to 12653)
  AUTHORS   van Nierop GP, de Vries AA, Holkers M, Vrijsen KR, Goncalves MA.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUL-2009) Molecular Cell Biology, Leiden University 
            Medical Center, Einthovenweg 20, Leiden, Zuid Holland 2333 ZC, The 
            Netherlands
REFERENCE   3  (bases 1 to 12653)
  TITLE     Direct Submission
REFERENCE   4  (bases 1 to 12653)
  AUTHORS   .
  TITLE     Direct Submission
COMMENT     SGRef: number: 1; type: "Journal Article"; journalName: "Nucleic 
            Acids Res."; date: "2009"; volume: "37"; issue: "17"; pages: 
            "5725-5736"
COMMENT     SGRef: number: 2; type: "Journal Article"; journalName: "Submitted 
            (14-JUL-2009) Molecular Cell Biology, Leiden University Medical 
            Center, Einthovenweg 20, Leiden, Zuid Holland 2333 ZC, The 
            Netherlands"
COMMENT     SGRef: number: 3; type: "Journal Article"
FEATURES             Location/Qualifiers
     source          1..12653
                     /mol_type="other DNA"
                     /organism="synthetic DNA construct"
     promoter        1216..2397
                     /label=EF-1-alpha promoter
                     /note="strong constitutive promoter for human elongation
                     factor EF-1-alpha"
     LTR             2505..2773
                     /label=5' LTR (truncated)
                     /note="truncated 5' long terminal repeat (LTR) from human
                     T-cell leukemia virus (HTLV) type 1"
     promoter        complement(2810..2828)
                     /label=T7 promoter
                     /note="promoter for bacteriophage T7 RNA polymerase"
     CDS             2895..3611
                     /label=hrGFP
                     /note="humanized Renilla green fluorescent protein"
     polyA_signal    complement(3646..3767)
                     /label=SV40 poly(A) signal
                     /note="SV40 polyadenylation signal"
     misc_feature    4062..4563
                     /label=HA-L
                     /note="left homology arm from the adeno-associated virus 
                     integration site (AAVS1) within intron 1 of the human 
                     PPP1R12C gene"
     misc_feature    4685..5521
                     /label=HA-R
                     /note="right homology arm from the adeno-associated virus 
                     integration site (AAVS1) within intron 1 of the human 
                     PPP1R12C gene"
     rep_origin      complement(8629..9017)
                     /direction=LEFT
                     /label=R6K gamma ori
                     /note="gamma replication origin from E. coli plasmid R6K;
                     requires the R6K initiator protein pi for replication"
     oriT            complement(9035..9325)
                     /direction=LEFT
                     /label=oriT
                     /note="origin of transfer for the bacterial F plasmid
                     (Frost et al., 1994)"
     CDS             complement(9381..10172)
                     /label=NeoR/KanR
                     /note="aminoglycoside phosphotransferase"
     misc_feature    10588..12626
                     /note="Arm 1; human chromosome 19 AAVS1 locus region"
ORIGIN
        1 acttagcgtt ggccacatag taggttctca aatacttgtt aataaataag tttgttcgag
       61 aagctgggca atgatattct acagctggaa gaagaaacat aatgatctag taattagctc
      121 aattaaaaat aaacgttctt ctttcctcag aggagcattt cccaaggcct gccttgatag
      181 ccatccaaaa aggccaagct catccaatct tgccctagat ttatgctaaa atgcagttac
      241 aatcgatagg atgacagaaa acgacagcac ttatttaaat ataataggca cttatttaaa
      301 taggagaagc tgtgacttca tagcaagtgt tggggttagg aaactgggtg gataaacttg
      361 ctgatgctgt agatcttagc ctctacatga gatcatgtgg aaaatctgaa agcattttag
      421 gttccttatg tttgcaatca aataactgta caccttttaa tttaaaaagt accatgaggc
      481 acacacacac actcgcagga actttttggc gtaacaaaac tagaattaga tctaaaagct
      541 aactgtagga ctgagtctat tctaaactga aagcctggac atctggagta ccagggggag
      601 atgacgtgtt acgggcttcc ataaaagcag ctggctttga atggaaggag ccaagaggcc
      661 agcacaggag cggattcgtc gctttcacgg ccatcgagcc gaacctctcg caagtccgtg
      721 agccgttaag gaggccccca gtcccgaccc ttcgccccaa gcccctcggg gtccccgggc
      781 ctggtactcc ttgccacacg ggaggggcgc ggaagccggg gcggaggagg agccaacccc
      841 gggctgggct gagacccgca gaggaagacg ctctagggat ttgtcccgga ctagcgagat
      901 ggcaaggctg aggacgggag gctgattgag aggcgaaggt acaccctaat ctcaatacaa
      961 cctttggagc taagccagca atggtagagg gaagattctg cacgtccctt ccaggcggcc
     1021 tccccgtcac cacccccccc aacccgcccc gaccggagct gagagtaatt catacaaaag
     1081 gactcgcccc tgccttgggg aatcccaggg accgtcgtta aactcccact aacgtagaac
     1141 ccagagatcg ctgcgttccc gccccctcac ccgcccgctc tcgtcatcac tgaggtggag
     1201 aagagcatgc gtgaggctcc ggtgcccgtc agtgggcaga gcgcacatcg cccacagtcc
     1261 ccgagaagtt ggggggaggg gtcggcaatt gaaccggtgc ctagagaagg tggcgcgggg
     1321 taaactggga aagtgatgtc gtgtactggc tccgcctttt tcccgagggt gggggagaac
     1381 cgtatataag tgcagtagtc gccgtgaacg ttctttttcg caacgggttt gccgccagaa
     1441 cacaggtaag tgccgtgtgt ggttcccgcg ggcctggcct ctttacgggt tatggccctt
     1501 gcgtgccttg aattacttcc acgcccctgg ctgcagtacg tgattcttga tcccgagctt
     1561 cgggttggaa gtgggtggga gagttcgagg ccttgcgctt aaggagcccc ttcgcctcgt
     1621 gcttgagttg aggcctggcc tgggcgctgg ggccgccgcg tgcgaatctg gtggcacctt
     1681 cgcgcctgtc tcgctgcttt cgataagtct ctagccattt aaaatttttg atgacctgct
     1741 gcgacgcttt ttttctggca agatagtctt gtaaatgcgg gccaagatct gcacactggt
     1801 atttcggttt ttggggccgc gggcggcgac ggggcccgtg cgtcccagcg cacatgttcg
     1861 gcgaggcggg gcctgcgagc gcggccaccg agaatcggac gggggtagtc tcaagctggc
     1921 cggcctgctc tggtgcctgg cctcgcgccg ccgtgtatcg ccccgccctg ggcggcaagg
     1981 ctggcccggt cggcaccagt tgcgtgagcg gaaagatggc cgcttcccgg ccctgctgca
     2041 gggagctcaa aatggaggac gcggcgctcg ggagagcggg cgggtgagtc acccacacaa
     2101 aggaaaaggg cctttccgtc ctcagccgtc gcttcatgtg actccacgga gtaccgggcg
     2161 ccgtccaggc acctcgatta gttctcgagc ttttggagta cgtcgtcttt aggttggggg
     2221 gaggggtttt atgcgatgga gtttccccac actgagtggg tggagactga agttaggcca
     2281 gcttggcact tgatgtaatt ctccttggaa tttgcccttt ttgagtttgg atcttggttc
     2341 attctcaagc ctcagacagt ggttcaaagt ttttttcttc catttcaggt gtcgtgagga
     2401 attatcgagc tctcccggga attcgatcgg cctctgagct attccagaag tagtgaggag
     2461 gcttttttgg aggcctaggc ttttgcaaaa agctcctcga tcgaggggct cgcatctctc
     2521 cttcacgcgc ccgccgccct acctgaggcc gccatccacg ccggttgagt cgcgttctgc
     2581 cgcctcccgc ctgtggtgcc tcctgaactg cgtccgccgt ctaggtaagt ttaaagctca
     2641 ggtcgagacc gggcctttgt ccggcgctcc cttggagcct acctagactc agccggctct
     2701 ccacgctttg cctgaccctg cttgctcaac tctacgtctt tgtttcgttt tctgttctgc
     2761 gccgttacag atccaagctc ctcgaggggg ggcccggtac ccaattcgcc ctatagtgag
     2821 tcgtattacg cgcgatcgag ctctcccaat actagatcgc atgcctgcag agctctagag
     2881 tcgacgaatt caccatggtg agcaagcaga tcctgaagaa caccggcctg caggagatca
     2941 tgagcttcaa ggtgaacctg gagggcgtgg tgaacaacca cgtgttcacc atggagggct
     3001 gcggcaaggg caacatcctg ttcggcaacc agctggtgca gatccgcgtg accaagggcg
     3061 cccccctgcc cttcgccttc gacatcctga gccccgcctt ccagtacggc aaccgcacct
     3121 tcaccaagta ccccgaggac atcagcgact tcttcatcca gagcttcccc gccggcttcg
     3181 tgtacgagcg caccctgcgc tacgaggacg gcggcctggt ggagatccgc agcgacatca
     3241 acctgatcga ggagatgttc gtgtaccgcg tggagtacaa gggccgcaac ttccccaacg
     3301 acggccccgt gatgaagaag accatcaccg gcctgcagcc cagcttcgag gtggtgtaca
     3361 tgaacgacgg cgtgctggtg ggccaggtga tcctggtgta ccgcctgaac agcggcaagt
     3421 tctacagctg ccacatgcgc accctgatga agagcaaggg cgtggtgaag gacttccccg
     3481 agtaccactt catccagcac cgcctggaga agacctacgt ggaggacggc ggcttcgtgg
     3541 agcagcacga gaccgccatc gcccagctga ccagcctggg caagcccctg ggcagcctgc
     3601 acgagtgggt gtaatagctc gagcggccgc ttcgagcaga catgataaga tacattgatg
     3661 agtttggaca aaccacaact agaatgcagt gaaaaaaatg ctttatttgt gaaatttgtg
     3721 atgctattgc tttatttgta accattataa gctgcaataa acaagttaac aacaacaatt
     3781 gcattcattt tatgtttcag gttcaggggg aggtgtggga ggttttttaa agcaagtaaa
     3841 acctctacaa atgtggatcc aattgcaatg atcatcatga cagatctgcg cgcgatcgat
     3901 cgacctgagg taattataac ccgggcccta tatatggatc caattgcaat gatcatcatg
     3961 acagatctgc gcgcgatcga tatcagcgct ttaaatttgc gcatgctagc tatagttcta
     4021 gaggtaccgg ttgttaacgt tagccggcta cgtatactcc ggagcacttc cttctcggcg
     4081 ctgcaccacg tgatgtcctc tgagcggatc ctccccgtgt ctgggtcctc tccgggcatc
     4141 tctcctccct cacccaaccc catgccgtct tcactcgctg ggttcccttt tccttctcct
     4201 tctggggcct gtgccatctc tcgtttctta ggatggcctt ctccgacgga tgtctccctt
     4261 gcgtcccgcc tccccttctt gtaggcctgc atcatcaccg tttttctgga caaccccaaa
     4321 gtaccccgtc tccctggctt tagccacctc tccatcctct tgctttcttt gcctggacac
     4381 cccgttctcc tgtggattcg ggtcacctct cactcctttc atttgggcag ctcccctacc
     4441 ccccttacct ctctagtctg tgctagctct tccagccccc tgtcatggca tcttccaggg
     4501 gtccgagagc tcagctagtc ttcttcctcc aacccgggcc cctatgtcca cttcaggaca
     4561 gcatgtttgc tgcctccagg gatcctgtgt ccccgagctg ggaccacctt atattcccag
     4621 ggccggttaa tgtggctctg gttctgggta cttttatctg tcccctccac cccacagtgg
     4681 ggccactagg gacaggattg gtgacagaaa agccccatcc ttaggcctcc tccttcctag
     4741 tctcctgata ttgggtctaa cccccacctc ctgttaggca gattccttat ctggtgacac
     4801 acccccattt cctggagcca tctctctcct tgccagaacc tctaaggttt gcttacgatg
     4861 gagccagaga ggatcctggg agggagagct tggcaggggg tgggagggaa gggggggatg
     4921 cgtgacctgc ccggttctca gtggccaccc tgcgctaccc tctcccagaa cctgagctgc
     4981 tctgacgcgg ccgtctggtg cgtttcactg atcctggtgc tgcagcttcc ttacacttcc
     5041 caagaggaga agcagtttgg aaaaacaaaa tcagaataag ttggtcctga gttctaactt
     5101 tggctcttca cctttctagt ccccaattta tattgttcct ccgtgcgtca gttttacctg
     5161 tgagataagg ccagtagcca gccccgtcct ggcagggctg tggtgaggag gggggtgtcc
     5221 gtgtggaaaa ctccctttgt gagaatggtg cgtcctaggt gttcaccagg tcgtggccgc
     5281 ctctactccc tttctctttc tccatccttc tttccttaaa gagtccccag tgctatctgg
     5341 gacatattcc tccgcccaga gcagggtccc gcttccctaa ggccctgctc tgggcttctg
     5401 ggtttgagtc cttggcaagc ccaggagagg cgctcaggct tccctgtccc ccttcctcgt
     5461 ccaccatctc atgcccctgg ctctcctgcc ccttccctac aggggttcct ggctctgctc
     5521 ttcagactga gccccgttcc cctgcatccc cgttcccctg catccccctt cccctgcatc
     5581 ccccagaggc cccaggccac ctacttggcc tggaccccac gagaggccac cccagccctg
     5641 tctaccaggc tgccttttgg gtggattctc ctccaactgt ggggtgactg cttggcaaac
     5701 tcactcttcg gggtatccca ggaggcctgg agcattgggg tgggctgggg ttcagagagg
     5761 agggattccc ttctcaggtt acgtggccaa gaagcagggg agctgggttt gggtcaggtc
     5821 tgggtgtggg gtgaccagct tatgctgttt gcccaggaca gcctagtttt agcactgaaa
     5881 ccctcagtcc taggaaaaca gggatggttg gtcactgtct ctgggtgact cttgattccc
     5941 ggccagtttc tccacctggg gctgtgtttc tcgtcctgca tccttctcca ggcaggtccc
     6001 caagcatcgc ccccctgctg tggctgttcc caagttctta gggtacccca cgtgggttta
     6061 tcaaccactt ggtgaggctg gtaccctgcc cccattcctg caccccaatt gccttagtgg
     6121 ctagggggtt gggggctaga gtaggagggg ctggagccag gattcttagg gctgaacaga
     6181 gaagagctgg gggcctgggc tcctgggttt gagagaggag gggctggggc ctggactcct
     6241 gggtccgagg gaggaggggc tggggcctgg actcctgggt ctgagggtgg agggactggg
     6301 ggcctggact cctgggtccg agggaggagg ggctggggcc tggactcgtg ggtctgaggg
     6361 aggaggggct gggggcctgg acttctgggt cttagggagg cggggctggg cctggacccc
     6421 tgggtctgaa tggggagagg ctgggggcct ggactccttc atctgagggc ggaagggctg
     6481 gggcctggcc tcctgggttg aatggggagg ggttgggcct ggactctgga gtccctggtg
     6541 cccaggcctc aggcatcttt cacagggatg cctgtactgg gcaggtcctt gaaagggaaa
     6601 ggcccattgc tctccttgcc cccctcccct atcgccatga caactgggtg gaaataaacg
     6661 agccgagttc atcccgttcc cagggcacgt gcggcccctt cacagcccga gtttccatga
     6721 cctcatgctc ttggccctcg tagctccctc ccgcctcctc cagatgggca gctttggaga
     6781 ggtgagggac ttggggggta atttatcccg tggatctagg agtttagctt cactccttcc
     6841 tcagctccag ttcaggtccc ggagcccacc cagtgtccac aaggcctggg gcaagtccct
     6901 cctccgaccc cctggacttc ggcttttgtc cccccaagtt ttggacccct aagggaagaa
     6961 tgagaaacgg tggcccgtgt cagcccctgg ctgcagggcc ccgtgcagag ggggcctcag
     7021 tgaactggag tgtgacagcc tggggcccag gcacacaggt gtgcagctgt ctcacccctc
     7081 tgggagtccc gcccaggccc ctgagtctgt cccagcacag ggtggccttc ctccaccctg
     7141 catagccctg ggcccacggc ttcgttcctg cagagtatct gctggggtgg tttccgagct
     7201 tgacccttgg aaggacctgg ctgggtttaa ggcaggaggg gctgggggcc aggactcctg
     7261 gctctgaagg aggaggggct ggaacctctt ccctagtctg agcactggaa gcgccacctg
     7321 tgggtggtga cgggggtttt gccgtgtcta acaggtacca tgtggggttc ccgcacccag
     7381 atgagaagcc ccctcccttc cccgttcact tcctgtttgc agatagccag gagtcctttc
     7441 gtggtttcca ctgagcactg aaggcctggc cggcctgacc actgggcaac caggcgtatc
     7501 ttaaacagcc agtggccaga ggctgttggg tcattttccc cactgtccta gcaccgtgtc
     7561 cctggatctg ttttcgtggc tccctctgga gtcccgactt gctgggacac cgtggctggg
     7621 gtaggtgcgg ctgacggctg tttcccaccc ccaggcctgc attgatgaga acctggaggt
     7681 ggtgcgcttc ttggtggagc agggcgccac tgtgaaccag gcagacaacg agggctggac
     7741 gccactgcac gtggccgcct cctgtggcta cctagatatc gccaggtgag gcaagggagg
     7801 gccgggcagg acctggtcgg ggtgggggcc tggaccctca gccctgacca gcccccaccc
     7861 ccaggtacct cctgagccac ggggccaaca tcgccgccgt caacagtgac ggggacctgc
     7921 ccctggacct ggccgagtcg gacgccatgg aggggctgct gaaggcggag atcgcccgcc
     7981 gaggtgggct ctggtgtgct gtgtgtgggg tgggggacac ctcctcaccc gtggtctcca
     8041 ggctgagagc tttagaggcg gcctgggcac cgaggctgac cctgcttcct aggattgtct
     8101 ttctttgtgc ctcagtttcc tcacctgtga aatgggggtg taggggcctg cctccaggat
     8161 tgcttggagc ccagcacacg cacaggatga gaactcaaac ccctaccaac tgggactgtc
     8221 aatccccctg agtaactgag gggattggaa tgccggggcg gggtgggtgg gtggagggac
     8281 tcacccagga gtgcgttagg taggattgct ggaaccctgc cgcaggtctt tctgggaggg
     8341 gatgcgttta cttggggggg agtaggggca tgcaggggtt gccagggact ggtctccctg
     8401 tcctctgaga ctcatcgtac cccaggagcc ttcatatgca tcctaggcct attaatattc
     8461 cggagtatac gtagccggct aacgttaaca accggtacct ctagaactat agctagcatg
     8521 cgcaaattta aagcgctgat atcgatcgcg cgcagatctg tcatgatgat cattgcaatt
     8581 ggatccatat atagggcccg ggttataatt acctcaggtc gacaattctg tcagccgtta
     8641 agtgttcctg tgtcactgaa aattgctttg agaggctcta agggcttctc agtgcgttac
     8701 atccctggct tgttgtccac aaccgttaaa ccttaaaagc tttaaaagcc ttatatattc
     8761 ttttttttct tataaaactt aaaaccttag aggctattta agttgctgat ttatattaat
     8821 tttattgttc aaacatgaga gcttagtacg tgaaacatga gagcttagta cgttagccat
     8881 gagagcttag tacgttagcc atgagggttt agttcgttaa acatgagagc ttagtacgtt
     8941 aaacatgaga gcttagtacg tgaaacatga gagcttagta cgtactatca acaggttgaa
     9001 ctgctgatca acagatcctc tacactagaa gggacgcacc gctagcagcg cccctagcgg
     9061 tatcctataa aaaaacacac cgcgccgcta gcagcacccc taatataaaa taatgttttt
     9121 tataaaaata gtcagtacca cccctacaaa acggtgtcgg cgcgttgttg tagccgcgcc
     9181 gacaccgctt ttttaaatat cataaagaga gtaagagaaa ctaatttttc ataacactct
     9241 atttataaag aaaaatcagc aaaaacttgt ttttgcgtgg ggtgtggtgc ttttggtggt
     9301 gagaaccacc aacctgttga gcctttttgt ggagtgggtt aaattatact agcgcgtttc
     9361 gaaccccaga gtcccgctca gaagaactcg tcaagaaggc gatagaaggc gatgcgctgc
     9421 gaatcgggag cggcgatacc gtaaagcacg aggaagcggt cagcccattc gccgccaagc
     9481 tcttcagcaa tatcacgggt agccaacgct atgtcctgat agcggtccgc cacacccagc
     9541 cggccacagt cgatgaatcc agaaaagcgg ccattttcca ccatgatatt cggcaagcag
     9601 gcatcgccat gtgtcacgac gagatcctcg ccgtcgggca tgcgcgcctt gagcctggcg
     9661 aacagttcgg ctggcgcgag cccctgatgc tcttcgtcca gatcatcctg atcgacaaga
     9721 ccggcttcca tccgagtacg tgctcgctcg atgcgatgtt tcgcttggtg gtcgaatggg
     9781 caggtagccg gatcaagcgt atgcagccgc cgcattgcat cagccatgat ggatactttc
     9841 tcggcaggag caaggtgaga tgacaggaga tcctgccccg gcacttcgcc caatagcagc
     9901 cagtcccttc ccgcttcagt gacaacgtcg agcacagctg cgcaaggaac gcccgtcgtg
     9961 gccagccacg atagccgcgc tgcctcgtcc tgcagttcat tcagggcacc ggacaggtcg
    10021 gtcttgacaa aaagaaccgg gcgcccctgc gctgacagcc ggaacacggc ggcatcagag
    10081 cagccgattg tctgttgtgc ccagtcatag ccgaatagcc tctccaccca agcggccgga
    10141 gaacctgcgt gcaatccatc ttgttcaatc atgcgaaacg atcctcatcc tgtctcttga
    10201 tcagatctct tcccaacctt accagagggc gccccagctg tccgaaatat tataaattat
    10261 cgcacacata aaaaccatgc tgttggtgtg tctattaaat cggcaactgt tgggaagggc
    10321 gatcggtgcg ggcctcttcg ctattacgcc agctggcgaa agggggatgt gctgcaaggc
    10381 gattaagttg ggtaacgcca gggttttccc agtcacgacg ttgtaaaacg acggcgcaag
    10441 gaatggtgca tgcaaggaga tggcgcccaa cagtcccccg gccacggggc ctgccaccat
    10501 acccacgccg aaacaagcgc tcatgacatt aacctataaa aataggcgta tcacgaggcc
    10561 ctttcgtctt caagaattgt tttaagctta agtaatgcaa aaggttgtcc tttaaaaaaa
    10621 aaaaaaatct ggccggtcgc ggcggctcac gcctgtaatc ccagcatttt gggaggccga
    10681 ggcagtcgga tcacgaggtc aggaattcga gaccagcctg gccaacatgg tgaaaccccg
    10741 tctctactaa aaaacaaaaa ttagccgggc gtggtggagc acgcctgtag tcccagctac
    10801 tcaggaggct gaggcaggag aatcgcttga acccgggagg cagagcttgc agtgagccga
    10861 catcgcgcca ctgcactcca gcctgggcga cagagcaagc ctccgtctca aaaacaacaa
    10921 caacaacaaa aaaaaacaaa actactgaca agttgctcta cttaacccaa agaaagtgaa
    10981 ggagaaagcg gctgcctcac cgcctagaca ttgagtcgcc ggatgtttca atgcctcatg
    11041 atacaataaa accacaaaaa ttttcgtaac agcagcagca acaacaacaa caaaagagaa
    11101 agagagaggg aaagaaacag gcctcgtggg atgcgcagtt tacgtctccg cgcaaaccca
    11161 aggacttcag agtgggtggg aaactcccac agcgcttggg aaacagtctg tagtctctgt
    11221 cccgattttg gcccttttct gtatgatttt tatgggactc ttcctgtcac aaagtgccag
    11281 ccaccttccc aatcttgagt tgggcgcggg atccgtaagg tgaagatcaa ggtgtgctca
    11341 tcgcttgggc ccgctgaaag gtgattcgcc ccccacctgc tggaactcct tgcccgggac
    11401 caccaatccc agcatgcctt gagagcgcgc gagggcctgg gcggttccca ggaggtccgg
    11461 gtgggcgcag gagaagcgcg ggccagtgaa agctctgaga gccctgtccc tgtggacact
    11521 gtgtcttggg ttcctttact cggtgtggct cagggattac cattagggag tggagtgtgg
    11581 atttctcttg ccccgagccc taaatgcctt ggggccctgc cttgcacccc actgtgcttt
    11641 taggggtgtg gccctgtggg ctacatttcc cagcgtgccc taggatcgtg gtcctgacct
    11701 tttcaccgca aatttcattt cccagcatgc cctgcgaggt cacccaggga agcttggaag
    11761 tggactgtct ttcatggctt ctaggttgcg gactcagttt cccatggtgc cctggtgaac
    11821 ccattcattc attcattcca aaaatatttg cgatcaggtt ctctcaggtt ctgttctaag
    11881 aaccgaggac aagtagtgca cagaagacaa aagatcccgc tctcgtggag cttatttcta
    11941 gttaaggggt caggaaaaaa accaaaataa ataaaaccca gctgggcatg gtggcttacg
    12001 ctcgtcatcc cagcaggatt acaggccgag gcgggcggat catgaggtca agagatcaag
    12061 accatcatgg ccaacatggt gaaatcccgt ctctactaaa aatataaaaa ttagcagggc
    12121 ggggtggcgc gcgcctgtta tcccagctac tctggggact gagccagaat tgcttgaacc
    12181 tgggaagcgg aggttgcagc gagccgatat cgcgccactg aactccagcg tggcgacaga
    12241 gcgagactcc gtctcaaaac aaagaaaaca aaataaaaca acaataacaa aacaactctg
    12301 cctctccccg cactccctcc cacgcggctg tccagtcgaa ttcctaactg ccccggggca
    12361 gtctgctatt catccccttt acccggtgct acacacttcc tagtatgccg tggggcaccc
    12421 ctccggcctg tagactccat ttcccagcat tccccggagg aggccctcat ctggcgattt
    12481 ccactgggcg cctcggagct gcggacttcc cagtgtgcat cggggcacag cgactcctgg
    12541 aagtggccaa gggccacttc tgctaatgga ctccatttcc cagcgctccc cgcgacctgc
    12601 ccagcacacc ctggggcagc gccgtgcgaa ttcagcacct gcacatgggg gtc
//
