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  • Mouse Osteoprotegerin/TNFRSF11B (Fc Tag) recombinant protein

Mouse Osteoprotegerin/TNFRSF11B (Fc Tag) recombinant protein

Cat.#: 502836

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Product Information

  • Product Name
    Mouse Osteoprotegerin/TNFRSF11B (Fc Tag) recombinant protein
  • Documents
  • Description
    Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. Inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local ratio between TNFSF11 and TNFRSF11B. May also play a role in preventing arterial calcification. May act as decoy receptor for TNFSF10/TRAIL and protect against apoptosis. TNFSF10/TRAIL binding blocks the inhibition of osteoclastogenesis.
  • Protein name
    Tumor necrosis factor receptor superfamily member 11B
  • Protein short names
    TNFRSF11B; TR1; OSTEOPROTEGERIN; MGC29565; OPG; OCIF
  • Uniprot ID
    Q3UK97
  • Gene Name
    Tnfrsf11b; Ocif; Opg
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the mouse Tnfrsf11b (NP_032790.3) (Met1-Leu401) was expressed with the Fc region of human IgG1 at the C-terminus.
  • Protein Species
    Mouse
  • Molecular weight
    The recombinant mouse Tnfrsf11b consists 618 amino acids and predicts a molecular mass of 70.2 kDa.
  • Purity
    > 95 % as determined by SDS-PAGE.
  • Validations

    Mouse Osteoprotegerin / TNFRSF11B Protein (Fc Tag)

    Mouse Osteoprotegerin / TNFRSF11B Protein (Fc Tag)

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"