Mouse CD96 (His Tag) recombinant protein
May be involved in adhesive interactions of activated T and NK cells during the late phase of the immune response. Promotes NK cell-target adhesion by interacting with PVR present on target cells. May function at a time after T and NK cells have penetrated the endothelium using integrins and selectins, when they are actively engaging diseased cells and moving within areas of inflammation (By similarity).
T-cell surface protein tactile
Protein short names
TACTILE; 1700109I12RIK; MGC22596; CD96; DKFZP667E2122
A DNA sequence encoding the mouse CD96 (Q3U0X8) extracellular domain (Met 1-Met 536) was expressed, fused with a C-terminal polyhistidine tag.
The secreted recombinant mouse CD96 comprises 526 amino acids and has a calculated molecular mass of 58 kDa. As a result of glycosylation, the apparent molecular mass of the recombinant protein is approximately 130-140 kDa in SDS-PAGE under reducing conditions.
> 90 % as determined by SDS-PAGE
1. Measured by its binding ability in a functional ELISA.
2. Immobilized recombinant Mouse CD96 at 10 μg/ml (100 μl/well) can bind mouse PVR with a linear range of 6.4-160 ng/ml.
Mouse CD96 Protein (His Tag) SDS-PAGE
Related Products / Services
- Recombinant Proteins
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- Human CD96 (His tag) recombinant protein$578.2
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