Human CD150 / SLAM / SLAMF1 (His Tag) recombinant protein

Cat.#: 500043

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Product Information

  • Product Name
    Human CD150 / SLAM / SLAMF1 (His Tag) recombinant protein
  • Documents
  • Description
    High-affinity self-ligand important in bidirectional T-cell to B-cell stimulation. SLAM-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAM signaling are likely to exist: one in which the inhibitor SH2D1A acts as a negative regulator and another in which protein-tyrosine phosphatase 2C (PTPN11)-dependent signal transduction operates.
  • Protein name
    Signaling lymphocytic activation molecule
  • Protein short names
    SLAM; SLAMF1; MGC151476; AA177906; CD150; CDW150; IPO-3; ESTM51; 4933415F16; MGC151472
  • Uniprot ID
    Q13291
  • Gene Name
    SLAMF1; SLAM
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human SLAM (NP_003028.1) precursor (Met 1-Pro 258) with a C-terminal polyhistidine tag was expressed.
  • Protein Species
    Human
  • Molecular weight
    The secreted recombinant human SLAM comprises 228 amino acids with a predicted molecular mass of 25.8 kDa. As a result of glycosylation, it migrates as an approximately 45-50 kDa band in SDS-PAGE under reducing conditions.
  • Purity
    > 97 % as determined by SDS-PAGE
  • Activity
    Measured by its ability to bind biotinylated recombinant human SH2D1A in a functional ELISA.
  • Validations

    Human CD150 / SLAM / SLAMF1 Protein (His Tag) SDS-PAGE

    Human CD150 / SLAM / SLAMF1 Protein (His Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"